Isolate, activate, and expand T cells

Rely on the same proven technology platform throughout mouse and human stages of your T cell research. Obtain a 100- to 1000-fold expansion of T cells within 9–14 days, with no need for feeder cells or antigen presenting cells (APCs). T cells exhibit properties comparable to in vivoactivated T cells.

Preserve T cell viability and optimal immune function

Dynabeads CD3/CD28 CTS (formerly known as Xcyte Dynabeads and Dynabeads ClinExVivo CD3/CD28) was developed to optimize ex vivo T cell expansion in translational research while preserving T cell viability and optimal immune function.

Designed to mimic in vivo activation and expansion, these ready-to-use Dynabeads are coated with antibodies directed against the TCR/CD3 and co-stimulatory CD28 receptors that are required for optimal T cell expansion.

The DynaMag CTS magnet is developed for optimal performance with the Dynabeads CD3/CD28 CTS technology, and allows you to work with large sample sizes (up to 10 L).

Diagram comparing in vivo activation and expansion with Dynabeads T cell activation

Figure 1. Diagram compares T cell activation with in vivo activation with Dynabeads.

Legal and Regulatory

In USA, Dynabeads CD3/CD28 CTS are available for clinical use only under an approved IND application. A Device Master File is held at the US Food and Drug Administration for cross-referencing in Investigational New Drug (IND) applications.

References on T cell expansion

Using Dynabeads for T cell expansion

Dynabeads allow for specific capture of biomolecules while undesired molecules don't bind. Gentle magnetic separation leaves unbound molecules in the solution and bead-bound molecules ready for downstream analysis.


See Dynabeads Cell Isolation & Expansion support within the Cell Analysis Support Center for  tips, troubleshooting help, and resources.

Services & Support

For Research Use Only. Not for use in diagnostic procedures.