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Insect Venom Allergy

For many insect venom-sensitized patients, an anaphylactic reaction after a sting is a traumatic event resulting in an altered quality of life. The purpose of venom hypersensitivity diagnosis is to classify a sting reaction by history, identify the underlying pathogenesis, and identify the offending insect. Systemic anaphylactic reactions are most often IgE mediated.1

Understanding Venom Allergy >

Who Should Be Tested

Diagnostic tests should be carried out in all patients with a history of a systemic sting reaction to detect sensitization. 

Venom Immunotherapy (VIT) is recommended as an option for the treatment of IgE-mediated bee and wasp venom allergy in patients who have had:2

  • A severe systemic reaction
  • A moderate systemic reaction and one or more of the following: concomitant pathology such as cardiovascular disease or mastocytosis, a high risk of future stings, or anxiety about future stings.

Venom Testing Opportunities

ImmunoCAPTM Whole Allergen

ImmunoCAP Whole Allergens provides an objective measurement of the circulating specific IgE antibodies and the sensitization to a specific whole allergen. Specific IgE antibodies can appear as a result of exposure to an allergen in atopic individuals. ImmunoCAP Whole Allergen measure IgE antibodies to specific allergens in human serum or plasma and allows quantitative measurements of a wide range of individual allergens. Over 550 different allergens are available for determinations.3

Allergy Testing

Conditions & Diseases

Understand allergic and autoimmune diseases.
 

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References
  1. Biló B, et al. Diagnosis of Hymenoptera venom allergy. Allergy. 2005; 60(11):1339-1349.
  2. Bonifazi F, et al. Prevention and treatment of hymenoptera venom allergy guidelines for clinical practice. P Allergy. 2005;60(12):1459-1470.
  3. PhadiaTM ImmunoCAPTM Specific IgE Directions for Use for the Phadia 250 Laboratory System. Issued September 2017.