Sample Preparation and Automation Solutions for Contaminant and Impurity Testing

Applied Biosystems PrepSEQ Residual DNA Sample Preparation Kit

PrepSEQ Residual DNA Sample Preparation Kits are optimized for consistent recovery of DNA and RNA from various sample matrices. The kit has flexible protocols for both manual and automated workflows to enable consistent, reliable recovery for even the most challenging samples. The PrepSEQ Residual DNA Sample Prep Kit can be used with the resDNASEQ quantitative residual host cell DNA kits that are available for CHO, Human, HEK293, E. coli, Vero, MDCK, NS0, and Pichia pastoris cell lines.

Thermo Scientific KingFisher Apex and Kingfisher Flex Sample Purification Instruments

We offer a high throughput solution for the automation of the PrepSEQ workflow to purify samples for residual host cell DNA analysis. The complete sample DNA and RNA extraction and 96-well preparation for qPCR analysis can be achieved in as little as three hours using PrepSEQ/resDNASEQ kits. The KingFisher Apex and KingFisher Flex Instruments automate the PrepSEQ workflow to help deliver reliable high DNA/RNA recovery with consistent performance, regardless of sample complexity.

Applied Biosystems PrepSEQ Nucleic Acid Sample Preparation Kit

The PrepSEQ Nucleic Acid Sample Preparation Kit is optimized for highly efficient, quantitative, and consistent recovery of DNA and RNA from diverse samples types, including cell culture, raw material (e.g., serum), and in-process downstream purification samples, such as column purification or bulk drug substance samples.

Applied Biosystems PrepSEQ 1-2-3 Nucleic Acid Extraction Kit

Conduct manual sample preparation for the extraction of DNA and RNA from mycoplasma cells, MMV isolates, and/or Vesivirus isolates. Minimizing cellular DNA and/or RNA in the final sample extraction is critical to mycoplasma DNA detection where high amounts of cellular DNA and RNA can cause PCR inhibition and high background. PrepSEQ 1-2-3 kits allow for sample cleanup of mycoplasma genomic DNA from research cell lines, stem cell lines, cellular, and tissue therapy samples with high efficiency. The workflow offers a rapid and easy to use protocol for results as little as 2 hours.

Automate Express Nucleic Acid Extraction System

We offer an easy-to-use benchtop instrument that enables hands-free automation of the nucleic acid extraction process for the MycoSEQ Mycoplasma Detection, ViralSEQ MMV Detection, and ViralSEQ Vesivirus Detection testing workflows. The instrument uses the established PrepSEQ nucleic acid extraction chemistry packaged into a cartridge format for quantitative recovery of DNA and RNA. The Automate Express System offers out-of-the-box automation for easy integration into existing workflows and lab configurations. There is minimal hands-on time with this closed system, allowing you to “load and go” with prefilled reagent cartridges and preprogrammed protocols. The Automate Express magnetic particle processor instrument offers low to medium throughput of up to 13 extractions in one run. 

PrepSEQ Express Nucleic Acid Extraction Kit

This ready-to-go kit contains pre-filled reagents and plastic tubes and tips to perform hands-free extraction of purified nucleic acid from 52 samples. The kit is designed for use on the AutoMate Express Nucleic Acid Extraction System. The cartridges utilize the established PrepSEQ nucleic acid extraction chemistry for quantitative recovery of DNA and RNA from diverse samples types, including cell culture, raw material, and in-process samples.