Custom Single-Use BioProcess Containers

The wide range of possible options with customized products has a direct impact on their practicality, availability, level of support, and cost. For this reason, we’ve developed an efficient customization Contract Review Procedure compliant to ISO 9001 to help meet your requirements.

Customize your BPC to fit your specific needs

There are three main categories of customized BPC assemblies:

BioProcess Containers

The most common custom options are changes to connectors, tubing type/length, and addition of components such as sterilizing filters. A less common level of customization involves modifying the standard ports, volume, and dimensions of a BPC chamber to match a specific non-standard outer container.

Fluid Transfer Assemblies

These range from a simple length of tubing with connectors at each end to more complex designs with several branches. They are normally used as accessories to BPC systems to increase the number of connections available or add functionality. Common customizations include changes to connectors, tubing type/length, and addition of components such as sterilizing filters.

BPC Manifolds

BPC manifolds consist of a number of BPCs linked together by a spine of tubing and connectors. There is normally a single connection at the inlet of the spine.The most common customizations include changes to connectors, tubing type/length, and addition of components such as sterilizing filters.

The level of customization depends on the functionality required, which then dictates the choice of components and the design characteristics of the chambers.

As the complexity and sophistication of the BPC system increases the time required to fabricate the system, and the customer’s commercial commitment also increases. To simplify the process, custom configurations are divided into two categories:

Made to order (MTO)

  • These designs utilize components from our standard component library.
  • Due to the size and diversity of the standard component library, selection guides are provided to define the available options.
  • The main advantages of selecting this type of customization include a simpler design process, shorter lead times, and greater cost-containment. For these reasons, most custom products are MTOs.
  • MTO products are specifically configured using established chamber designs combined with components from our standard component library.
  • The scope of outer container MTOs is limited to simple and minor modifications to the fit or finish of existing designs that do not change the internal dimensions or the interface with the matching BPC assembly.

Engineered to order (ETO)

  • ETO products typically include chambers with unique dimensions, matching a specific outer container, which are not part of our library of qualified and validated designs. Thus our engineering, manufacturing, and validation teams actively participate in the conceptualization, design, fabrication, and qualification of these unique chambers to meet the established criteria of our standard chamber designs.
  • ETOs also encompass non-standard components. Non-standard components may not be accompanied by the same level of vendor-supplied documentation.
  • The final ETO category involves customized outer support containers, bins, shippers, racks, and dollies. When major structural modifications to existing or unique designs are required, the ETO-related processes of design, fabrication, qualification, and validation

There are three main categories of customized BPC assemblies:

BioProcess Containers

The most common custom options are changes to connectors, tubing type/length, and addition of components such as sterilizing filters. A less common level of customization involves modifying the standard ports, volume, and dimensions of a BPC chamber to match a specific non-standard outer container.

Fluid Transfer Assemblies

These range from a simple length of tubing with connectors at each end to more complex designs with several branches. They are normally used as accessories to BPC systems to increase the number of connections available or add functionality. Common customizations include changes to connectors, tubing type/length, and addition of components such as sterilizing filters.

BPC Manifolds

BPC manifolds consist of a number of BPCs linked together by a spine of tubing and connectors. There is normally a single connection at the inlet of the spine.The most common customizations include changes to connectors, tubing type/length, and addition of components such as sterilizing filters.

The level of customization depends on the functionality required, which then dictates the choice of components and the design characteristics of the chambers.

As the complexity and sophistication of the BPC system increases the time required to fabricate the system, and the customer’s commercial commitment also increases. To simplify the process, custom configurations are divided into two categories:

Made to order (MTO)

  • These designs utilize components from our standard component library.
  • Due to the size and diversity of the standard component library, selection guides are provided to define the available options.
  • The main advantages of selecting this type of customization include a simpler design process, shorter lead times, and greater cost-containment. For these reasons, most custom products are MTOs.
  • MTO products are specifically configured using established chamber designs combined with components from our standard component library.
  • The scope of outer container MTOs is limited to simple and minor modifications to the fit or finish of existing designs that do not change the internal dimensions or the interface with the matching BPC assembly.

Engineered to order (ETO)

  • ETO products typically include chambers with unique dimensions, matching a specific outer container, which are not part of our library of qualified and validated designs. Thus our engineering, manufacturing, and validation teams actively participate in the conceptualization, design, fabrication, and qualification of these unique chambers to meet the established criteria of our standard chamber designs.
  • ETOs also encompass non-standard components. Non-standard components may not be accompanied by the same level of vendor-supplied documentation.
  • The final ETO category involves customized outer support containers, bins, shippers, racks, and dollies. When major structural modifications to existing or unique designs are required, the ETO-related processes of design, fabrication, qualification, and validation

Step-by-step custom product procedure

Requirements are recorded on a Product Brief Form (PBF) which starts the process (Step 1).

This process includes preparing an engineering drawing (Step 2) and obtaining customer approval (Step 3) prior to a final price (Step 4). We require an order (Step 5) before manufacturing (Step 6) is initiated or a firm delivery date given (Step 7).

The length of time the entire process takes depends on the complexity of the product, approval time, availability of materials, and current manufacturing capacity. A made-to-order (MTO) product has the shortest and most predictable lead-time. An estimation can be provided during the initial discussion.

This starts with a discussion with your Thermo Fisher Scientific representative regarding your application and requirements. We’ll advise you of available options and the most suitable choices. Requirements are recorded on a Product Brief Form (PBF), which starts the process.

We then prepare an engineering drawing.

Customer approval is obtained.

Upon customer approval a final price is given.

Order is placed by the customer.
We require an order before manufacturing is initiated or a firm delivery date given.

Product is assembled and irradiated.

Product is delivered to the customer.

This starts with a discussion with your Thermo Fisher Scientific representative regarding your application and requirements. We’ll advise you of available options and the most suitable choices. Requirements are recorded on a Product Brief Form (PBF), which starts the process.

We then prepare an engineering drawing.

Customer approval is obtained.

Upon customer approval a final price is given.

Order is placed by the customer.
We require an order before manufacturing is initiated or a firm delivery date given.

Product is assembled and irradiated.

Product is delivered to the customer.


Specialty BioProcess Containers

The Harvestainer BPC is part of a closed, self-contained, single-use solution for harvesting and separating cell cultures grown on microcarrier beads.

The Powdertainer II BPC is specifically designed for powder containment and dust-free powder transfer operations.

The Three60 Sampling System allows you to take samples of your product with minimal effort in a closed system.