Targeted MS Quantitation

Consolidate your mass spectrometry (MS) laboratory with robust support for targeted quantitation and screening workflows in biopharma, environmental, and food safety sectors.

Connect instruments, users, and data in a centralized scalable server-based system, providing remote data access and central management of methods, templates, and reports. Full support for GMP compliance helps ensure data integrity, traceability, and verification throughout the data lifecycle. Native control of Thermo Scientific MS instruments, including single quadrupole, triple quadrupole and high-resolution accurate mass (HRAM), enables robust instrument operations.

Thermo Scientific Chromeleon Chromatography Data System (CDS) Software combines with industry-leading Thermo Scientific MS instrumentation to deliver an outstanding solution for targeted MSⁿ quantitation workflows.

Customer testimonial
"When we perform lead selection studies, the first thing is to determine if our candidate molecules are aggregating, along with their identities. We can do that in a single experiment with native SEC(UV)-MS and Chromeleon Software, and it’s a matter of seconds screening through the results."

- Dr. Dan Bach Kristensen, Principal Scientist, Symphogen

Built for MS workflows

Chromeleon Software supports targeted quantitation and screening MS workflows by providing a comprehensive solution for data acquisition, processing, and reporting. See how the software facilitates advanced data analysis and integrates seamlessly with other software tools to enhance the efficiency and reliability of your MS workflows. Examples include:

• Bioanalysis: Take advantage of simultaneous MS data acquisition, automated system suitability testing, spectral library integration, and data exchange with Thermo Scientific Watson LIMS.
• Intact proteins: Achieve high-quality results with optimized algorithms for both isotopically resolved and unresolved data, MS_¹ - MS_³ targeted library searching, and deliver high-throughput, accurate results.
• Multi-Attribute Method (MAM): Combine the flexibility of Thermo Scientific BioPharma Finder Software with compliance-ready Chromeleon Software to deliver a powerful MAM workflow.
• Dioxin, PCBs, and POPs analysis: Use built-in advanced internal standard techniques for accurate quantitation in complex matrices and automate sequence creation, calculations and reporting.
• PFAS analysis: Combine Chromeleon Software with Thermo Scientific Compound Discoverer Software for compliant MS data acquisition, advanced discovery, identification, and targeted processing, and reporting.
• Pesticide analysis: Utilize out-of-the-box workflows for fast and simple processing with tailored view settings, automated cross-confirmation, and adherence to SANTE guidelines.

Single software solution

Increase productivity with a single software solution for your entire laboratory and eliminate the complexity of multiple data systems to simplify training, streamline workflows, and reduce manual processes across your lab.

Supporting a broad range of MS and chromatography techniques within one intuitive platform, the consistent user experience spans all analyses—regardless of deployment model—and includes complete coverage from instrument control to data acquisition, processing, and reporting for both front-end separation and MS detection.

Control and access from anywhere

Keep your operations running smoothly and securely, whether working in the lab or remotely, Deliver secure, remote access to instruments and data, making it easy to monitor runs, review results, and manage workflows from anywhere.

Reduce IT overhead with streamlined system management using tools like the built-in updater to automate centralized rollout of maintenance packages, operating system updates, antivirus updates, among others, across the entire installation.

Help ensure data security with comprehensive system access control, auditing, and reporting using powerful querying capabilities facilitated by automated, centralized data storage with a secure relational database.

Built-in resilience and scalability

Achieve resilient, scalable performance across your laboratory operations. Designed for continuous uptime with zero data loss, the software features best-in-class automated network failure protection to keep your laboratory running and protect your data.

Its flexible architecture scales effortlessly from small, on-premise installations to large, multi-site deployments—on-premise, in the cloud, or virtual—without the need for reinstallation—while maintaining a consistent user experience.

Safeguard your data at every stage with robust network architecture and multi-layered security, eliminating single points of failure. With Chromeleon Software, your lab stays secure, connected, and ready to grow.

Enabling regulatory compliance

Chromeleon Software is designed from the ground up to help MS and chromatography labs simplify achieving, maintaining and demonstrating compliance to rigorous regulatory standards such as GxP, ISO, and 21 CFR Part 11. It provides powerful tools to help ensure data integrity, including extensive user access controls, comprehensive time-stamped audit trails, and result versioning capabilities. Electronic signatures and automated reporting enable efficient data review by exception, allowing for quick identification and resolution of discrepancies. These features work together to support laboratories in maintaining secure, traceable, and compliant workflows.