Search Thermo Fisher Scientific
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Thermo Fisher Scientific MDi technology combines advanced monodisperse particle platforms with bioinert hardware. MDi technology can be found in our Thermo Scientific SurePac Bio SEC MDi columns, and our Thermo Scientific ProPac 3R SAX and SCX columns.
SurePac Bio 550 SEC MDi columns - the 3 µm monodisperse silica provides superior resolution of adeno associated virus (AAV) and aggregates in cell and gene therapy applications.
ProPac 3R SAX and SCX columns - our proprietary 3 µm monodisperse polymeric technology which supports the delivery of reproducible, high resolution and robust strong anion and strong cation exchange chromatography separations for proteins, monoclonal antibodies, AAV, and other emerging modalities.
In chromatography column technology, the choice of particle size and distribution is crucial in achieving optimal separation efficiency and reliable results. Monodisperse particles deliver reproducibility, efficiency, enhanced resolution, and throughput, making them a superior choice in many chromatography applications.
Inert hardware refers to the use of materials that eliminate interactions with the sample, ensuring sample integrity and recovery. This type of hardware is particularly advantageous in biopharmaceutical analysis, where the accuracy and reliability of results are crucial. By reducing unwanted interactions, inert hardware helps to maintain sample integrity, prevent degradation or adsorption, and promote injection-to-injection reproducibility.
ProPac 3R SCX and SAX 3 μm columns provide the reproducibility, resolution, and robustness needed for protein characterization. These columns are ideal for charge variant analysis and recommended for use with therapeutic proteins, monoclonal antibodies (mAbs), antibody drug conjugates (ADCs), and biosimilars.
Designed with bioinert materials to reduce secondary interactions, our ProPac 3R SCX and SAX columns deliver the performance you need over a broad range of pH's, temperatures, and mobile phase compositions with excellent recovery and low carryover.
SurePac Bio 550 SEC MDi columns are exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process.
Designed with bioinert materials to reduce secondary interactions, SurePac Bio 550 SEC MDi columns are ideal for AAV gene therapeutics analysis and offers excellent selectivity due to the dedicated smaller particle (3 µm) size combined with wide-pore (550Å) for separating monomeric AAVs from aggregates based on their size differences.
For Research Use Only. Not for use in diagnostic procedures.