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Application Title Year
Transcriptional profiling Annatto (Bixa orellana) δ-TCT Supplementation Protection against Embryonic Malformations through Alterations in PI3K/Akt-Cyclin D1 Pathway  2019
Transcriptional profiling Context dependent roles for RB-E2F transcriptional regulation in tumor suppression  2019
Transcriptional profiling Decidual Interleukin-22-Producing CD4+ T Cells (Th17/Th0/IL-22+ and Th17/Th2/IL-22+, Th2/IL-22+, Th0/IL-22+), Which Also Produce IL-4, Are Involved in the Success of Pregnancy  2019
Tracking gene expression change resulting from injury eIF2B activator prevents neurological defects caused by a chronic integrated stress response  2019
Comparison of mRNA and protein expression levels Multiplexing Protein and Gene Level Measurements on a Single Luminex Platform.  2019
Tracking gene expression change resulting from injury Synthetic CpG-ODN rapidly enriches immune compartments in neonatal chicks to induce protective immunity against bacterial infections  2019
Transcriptional profiling Bead-based RNA multiplex panels for biomarker detection in oncology samples.  2018
Transcriptional profiling Comparison of Mesenchymal Stromal Cells Isolated from Murine Adipose Tissue and Bone Marrow in the Treatment of Spinal Cord Injury  2018
Transcriptional profiling Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells.  2018
Differential gene expression in response to medication Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine  2018
Differential gene expression in response to medication Development of screening method for intranasal influenza vaccine and adjuvant safety in preclinical study.  2018
Differential gene expression in response to medication Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054  2018
Differential gene expression in response to medication/treatment Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy  2018
Differential gene expression in response to medication/treatment Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles  2018
Tracking gene expression change resulting from injury Evidence for Genetic Contribution to Variation in Posttraumatic Osteoarthritis in Mice.  2018
Transcriptional profiling GAP43, a novel metastasis promoter in non-small cell lung cancer  2018
Tracking gene expression change resulting from injury Identification of mRNA of the Inflammation-associated Proteins CXCL8, CXCR2, CXCL10, CXCR3, and β-Arrestin-2 in Equine Wounded Cutaneous Tissue: a Preliminary Study  2018
Differential gene expression in response to medication Increased AURKA Gene Copy Number Correlates with Poor Prognosis and Predicts the Efficacy of High-dose Interferon Therapy in Acral Melanoma  2018
Differential gene expression in response to medication Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus  2018
Differential gene expression in response to medication/treatment Modeling for influenza vaccines and adjuvants profile for safety prediction system using gene expression profiling and statistical tools.  2018
Transcriptional profiling Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material  2018
Differential gene expression in response to medication Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus  2018
Differential gene expression in response to medication/treatment Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents  2018
Transcriptional profiling RNase If -treated quantitative PCR for dsRNA quantitation of RNAi trait in genetically modified crops.  2018
Differential gene expression in response to medication/treatment TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma  2018
Tracking gene expression change resulting from injury WNT SIGNALING REGULATES AIRWAY EPITHELIAL STEM CELLS IN ADULT MURINE SUBMUCOSAL GLANDS  2018
Transcriptional profiling A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae.  2017
Differential gene expression in response to medication Analysis of NRAS gain in 657 patients with melanoma and evaluation of its sensitivity to a MEK inhibitor.  2017
Transcriptional profiling Assessment of vascularity in glioblastoma and its implications on patient outcomes.  2017
Transcriptional profiling CD31, a Valuable Marker to Identify Early and Late Stages of T Cell Differentiation in the Human Thymus.  2017
Differential gene expression in response to medication CFTR Influences Beta Cell Function and Insulin Secretion Through Non-Cell Autonomous Exocrine-Derived Factors.  2017
Transcriptional profiling Comparative Analysis of Vertebrate Diurnal/Circadian Transcriptomes  2017
Differential gene expression in response to medication Comparison between tocotrienol and omeprazole on gastric growth factors in stress-exposed rats.  2017
Differential gene expression in response to medication/treatment Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.  2017
Transcriptional profiling Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis  2017
Tracking gene expression change resulting from injury Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon.  2017
Transcriptional profiling Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus.  2017
Transcriptional profiling Identification of coexistence of BRAF V600E mutation and EZH2 gain specifically in melanoma as a promising target for combination therapy.  2017
Comparison of mRNA and protein expression levels Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.  2017
Differential gene expression in response to medication/treatment Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling  2017
Differential gene expression in response to medication/treatment INHIBITORY EFFECT OF EMODIN ON RAW 264.7 ACTIVATED WITH DOUBLE STRANDED RNA ANALOGUE POLY I:C  2017
Transcriptional profiling Interchangeable Roles for E2F Transcriptional Repression by the Retinoblastoma Protein and p27KIP1-Cyclin- Dependent Kinase Regulation in Cell Cycle Control and Tumor Suppression.  2017
Transcriptional profiling Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control.  2017
Tracking gene expression change resulting from injury Peripheral Blood Gene Expression Changes Associated With Primary Graft Dysfunction After Lung Transplantation.  2017
Transcriptional profiling Prognostic value of a 25-gene assay in patients with gastric cancer after curative resection.  2017
Differential gene expression in response to medication/treatment Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.  2017
Comparison of mRNA and protein expression levels Syndecan-1 Acts as an Important Regulator of CXCL1 Expression and Cellular Interaction of Human Endometrial Stromal andTrophoblast Cells  2017
Transcriptional profiling The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages.  2017
Transcriptional profiling The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors  2017
Differential gene expression in response to medication/treatment Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study. Bunya   2017
Differential gene expression in response to medication/treatment Ursodeoxycholic acid protects cardiomyocytes against cobalt chloride induced hypoxia by regulating transcriptional mediator of cells stress hypoxia inducible factor 1α and p53 protein.  2017
Differential gene expression in response to medication Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration  2017
Comparison of QuantiGene to qPCR A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo.  2016
Transcriptional profiling A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation  2016
Transcriptional profiling A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.  2016
Transcriptional profiling Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips  2016
Differential gene expression in response to medication/treatment Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies.  2016
Differential gene expression in response to medication High-content molecular profiling of T-cell therapy in oncology  2016
Transcriptional profiling Longitudinal Claudin Gene Expression Analyses in Canine Mammary Tissues and Thereof Derived Primary Cultures and Cell Lines  2016
Review of multiple methods Signal Improvement Strategies for Fluorescence Detection of Biomacromolecules.  2016
Comparison of mRNA and protein expression levels TLR4 inhibitor attenuates amyloid-beta-induced angiogenic and inflammatory factors in ARPE-19 cells: Implications for age-related macular degeneration.  2016
Transcriptional profiling APOE-modulated Abeta-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.  2015
Tracking gene expression change resulting from injury/disease Brain transcriptome profiles in mouse model simulating features of post-traumatic stress disorder.  2015
Tracking gene expression change resulting from injury/disease Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.  2015
Tracking gene expression change resulting from injury/disease Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes.  2015
Tracking gene expression change resulting from injury/disease Differential Specificity of Interferon-alpha Inducible Gene Expression in Association with Human Immunodeficiency Virus and Hepatitis C Virus Levels and Declines in vivo.  2015
Transcriptional profiling Gene Expression in Hepatocellular Carcinoma: Pilot Study of Potential Transarterial Chemoembolization Response Biomarkers  2015
Tracking gene expression change resulting from injury/disease Genetic Loci that Regulate Ectopic Calcification in Response to Knee Trauma in LG/J by SM/J Advanced Intercross Mice  2015
Transcriptional profiling High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer  2015
Transcriptional profiling HIV-associated mucosal gene expression: region-specific alterations.  2015
Transcriptional profiling Identification of Pathways Mediating Growth Differentiation Factor5-Induced Tenogenic Differentiation in Human Bone Marrow Stromal Cells  2015
Transcriptional profiling Individual bile acids have differential effects on bile acid signaling in mice.  2015
Tracking gene expression change resulting from injury/disease INHBA overexpression indicates poor prognosis in urothelial carcinoma of urinary bladder and upper tract.  2015
Transcriptional profiling Metabolic markers associated with high mannose glycan levels of therapeutic recombinant monoclonal antibodies.  2015
Tracking gene expression change resulting from injury/disease Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung.  2015
Tracking gene expression change resultinng from injury/disease Recurrent amplification of MYC and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer.  2015
Transcriptional profiling SHP-1-Dependent Macrophage Differentiation Exacerbates Virus-Induced Myositis.  2015
Tracking gene expression change resulting from injury/disease The effects of orchidectomy and supraphysiological testosterone administration on trabecular bone structure and gene expression in rats.  2015
Transcriptional profiling TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells  2015
Tracking gene expression change resulting from medication/treatment Whole Grain Oats Improve Insulin Sensitivity and Plasma Cholesterol Profile and Modify Gut Microbiota Composition in C57BL/6J Mice  2015