The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
AT225; AT591; CMT1D; CMT4E; DKFZp686J1957; E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response 2 (Krox-20 homolog, Drosophila); Early growth response protein 1; Early growth response protein 2; EGR-1; EGR-2; FLJ14547; Krox-20 homolog; KROX-20, Drosophila, homolog (early growth response-2); KROX-20, Drosophila, homolog early growth response-2; Krox-24 nuclear protein; KROX20; Nerve growth factor-induced protein A; NGFI-A; TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268, EGR1, EGR2; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-20; Zinc finger protein Krox-24