Metabolite Detection, Quantitation, and Characterization

Leading Thermo Scientific Orbitrap-based mass spectrometers provide the high-resolution, accurate-mass (HRAM) measurements and sensitivity for highly reproducible untargeted and targeted analysis of metabolomics and lipidomics samples. Fast data acquisition and polarity switching maximize productivity by detecting both positive and negative ions in a single analysis. For routine and well characterized metabolites, the TSQ series of triple quadrupole MS systems provides unrivaled flexibility and sensitivity for SRM-based targeted quantitation of metabolites.

Obtain valuable quantitative insights from small- to large-scale studies across a variety of applications from untargeted, semi-targeted to targeted metabolomics studies. With optimized methods, the Thermo Scientific Orbitrap Exploris 240 mass spectrometer delivers a fast turnaround of sample to results with operational simplicity. Best-in-class performance together with Thermo Scientific AcquireX intelligent data acquisition delivers a fast track to confident results, all within a compact footprint, so you can go beyond with everyday versatility.

Obtain maximum insights on your most complex compounds and biological systems. With new innovations that deliver the experimental versatility to address chemical diversity, built-in AcquireX intelligent data acquisition strategy to collect more meaningful data and Real-Time Library Search for intellgent MSⁿ for structural elucidation, the Thermo Scientific Orbitrap IQ-X Tribrid mass spectrometer redefines untargeted metabolomics, accelerating your path to real biological results so you can drive your science beyond today’s discovery.

Designed for GC separations, the Thermo Scientific Orbitrap Exploris GC 240 mass spectrometer provides highly accurate data for quantification of all detectable compounds with high specificity and selectivity. The system has a wide dynamic range and excellent resolution for the simultaneous quantitation and confirmation of both high- and low-abundance metabolites.

For routine well characterized metabolites, the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer exceeds even the most stringent analytical requirements with superb sensitivity, speed and dynamic range for SRM-based targeted metabolomics applications.

For routine well characterized metabolites amenable to GC separations, the Thermo Scientific TSQ 9000 triple quadrupole GC-MS/MS delivers the highest productivity with superb sensitivity, speed, and dynamic range for SRM-based quantitation of targeted metabolomics applications.