Thermo Fisher Scientific is your provider in purification.
At Thermo Fisher Scientific, we are here to help you improve your purification process efficiency. In a complex world of biopharmaceuticals, vaccines, and gene therapies, you need a provider that is as focused as you are on delivering results. Our comprehensive resin portfolio is designed to help deliver innovative solutions that are scalable, and easily integrated into your platform to improve your process efficiency.
Enabling high purity, helping deliver superior resolution, and designed for high throughput applications, our novel CaptureSelect and POROS resin technologies address today’s challenges in your purification workflow.
Anion and cation exchange resins
Thermo Scientific POROS anion exchange and cation exchange resins are the industry standard for large-scale polish chromatography applications. These POROS resins allow target molecule binding and impurity removal over a broad range of process conditions, thereby increasing process flexibility and manufacturing throughput.
Affinity chromatography resins
Our affinity resins are designed to deliver high purity and high yield of your target molecule in a single capture step. They are scalable and useful from bench-scale process development to commercial manufacturing of antibody therapeutics, biosimilars and recombinant proteins, vaccines, and gene therapies.
Hydrophobic interaction chromatography (HIC) resins
Browse our suite of POROS HIC resins offering a differentiating range in hydrophobicity suitable for bind/elute and flow-through applications. These resins can be utilized at lower salt concentrations for the purification of a wide variety of biomolecules.
The manufacture of complex biotherapeutics requires novel purification strategies. Our custom ligand and chromatography resin services enable the development of innovative purification resins.
Cell and gene therapies
To support the manufacturing of cell and gene therapies, we’ve developed innovative chromatography solutions, specifically designed to improve the downstream purification of mRNA and viral vectors such as the Adeno-Associated Virus (AAV), lentivirus, and Adv5.
Our CaptureSelect antibody subdomain-specific affinity chromatography resins are developed for the downstream purification of novel antibody modalities, such as bi-specific monoclonal antibodies, Fab fragments and Fc-fusion proteins, and can facilitate the process scale purification of a variety of antibody formats for commercial production of therapeutics.
Biosimilars and recombinant proteins
We’ve developed a unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins.
Thermo Scientific CaptureSelect and POROS resin technologies address purification challenges in the vaccine production workflow. We offer a variety of efficient and scalable resins for affinity, ion exchange, and hydrophobic interaction chromatography applications.
With the potential to cure genetic disorders, gene therapies look set to revolutionize the field of medicine, and adeno-associated viruses have emerged as the vector of choice.
Discussion of aggregate clearance and viral clearance strategy on POROS HIC resins with novel ethyl and benzyl chemistries for the successful polish of mAbs A and B.
An overview of how new approaches to the manufacture of biosimilars have the potential to support sustainable access to critical non-monoclonal antibody biosimilars.
With demand for the large-scale production of clinical-grade mRNA suddenly surging, developers need fast, efficient, and highly scalable methods for mRNA purification.
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing:
Pharmaceutical Grade Reagent. For Manufacturing and Laboratory Use Only.