Gene expression-based high-throughput screening (HTS)

In drug discovery, time is money. Fast-track your discovery using the QuantiGene™ Singleplex HT Assay, which enables gene expression-based high-throughput screening of thousands of compounds every day. The assay's ELISA-like workflow is amenable to automation and does not require RNA purification or extensive assay optimization. The extremely robust QuantiGene Singleplex HT Assay is hybridization-based and uses no enzymes; instead, it relies on branched DNA technology for signal amplification and luminescence for signal readout.

QuantiGene Singleplex HT Assay capture plate
Unique benefits
  • High throughput: simple ELISA-like workflow is easily automated with liquid handling and dispensing platforms, with no RNA purification needed.
  • Robust and reproducible: high Z'-factors are typically attained with the QuantiGene Singleplex HT Assay, giving you more confidence in your hits.
  • Easy to use: no optimization of probe sets is required, sample preparation is minimal, and 384-well plate format allows for direct transfer of cells cultured in 384-well plates.