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Consistent, accurate assay performance—right out of the box

The Applied Biosystems resDNASEQ Residual Host Cell DNA kit offers a complete sample-to-results solution, including a highly-characterized genomic DNA standard*, for accurate validation of sensitivity and specificity. The kits are designed to detect fragmented and unfragmented DNA resulting in confident quantitation. Developed using rich bioinformatics and a sophisticated primer/probe design pipeline, then internally validated to help meet performance standards, resDNASEQ assays deliver highly accurate and consistent results – kit-to-kit, lot-to-lot, and year-to-year.

resDNASEQ kits include:

* Not included in some dPCR kits

resDNASEQ kits were designed to meet or exceed regulatory guidelines.


Why choose a commercial kit for residual DNA testing?

The overall performance of the resDNASEQ method, including sensitivity, accuracy, precision, range, and linearity meets or exceeds the example described in USP <509>.

 

Implementation of a fully integrated testing solution can reduce the expense and effort in procurement of assay components from multiple vendors and qualification of critical reagents that is required for in-house developed assays.


resDNASEQ quantitative DNA portfolio

The resDNASEQ residual host cell DNA quantitation system offers a robust portfolio of real-time and digital PCR assay kits to measure residual DNA levels from a large variety of host cell lines--including the plasmid DNA kanamycin resistance gene-- used in the production of biopharmaceutical products. 

resDNASEQ Quantitative 
CHO DNA kit




qPCR    dPCR

resDNASEQ Quantitative
E. coli DNA kit


 

 qPCR    dPCR

resDNASEQ Quantitative
HEK293 DNA kit




 qPCR

resDNASEQ Quantitative
Human DNA kit




 qPCR

resDNASEQ Quantitative
MDCK DNA kit


 

 qPCR

resDNASEQ Quantitative
NS0 DNA kit


 

 qPCR

resDNASEQ Quantitative
Pichia pastoris DNA kit

 

qPCR

resDNASEQ Quantitative
Sf9/Baculovirus DNA kit


 

 qPCR    dPCR

resDNASEQ Quantitative
Vero DNA kit




 qPCR

resDNASEQ Quantitative
E1A DNA Fragment Length kit

 

qPCR    dPCR

The Applied Biosystems resDNASEQ Quantitative E1A DNA Fragment Length Kit can be used in combination with the resDNASEQ Quantitative HEK293 DNA Kit to measure the length of residual E1A DNA fragments that are transformed into the HEK293 cell line. The workflow can use the same sample as for the resDNASEQ Quantitative HEK293 DNA Kit.

Discover our residual plasmid DNA quantitation solution

On-demand webinar: Quantitating Residual Host Cell and Plasmid DNA in a Biotherapeutic Manufacturing Workflow

Fast Facts: Robust quantitation of residual host cell and plasmid DNA & oncogenic fragments in HEK-based viral vector manufacturing

On-demand webinar: Simplify residual DNA quantitation in viral vector production: qPCR and dPCR tools


Request a technical consultation

No matter your questions, we are here to help. Our experienced team of scientists and technical specialists is ready to assist you in choosing the right solution and products. Complete this form to start the conversation.
 

 


Shop DNA quantitation kits

Analytics Knowledge Hub


Explore the Analytics Knowledge Hub from Thermo Fisher Scientific, providing a robust collection of webinars, articles, eBooks, infographics, and other digital resources to help you optimize the use of our products in your bioprocess workflow.
 

Additional resources

Enhance your bioprocessing knowledge with educational content to help you understand issues, solve problems, and make solid decisions.

Deep dive into a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing.

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