Accurate apoptosis analysis in your choice assays
Many different approaches are used in the study of programmed cell death, or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach for accurate assessment. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery.
We offer a wide array of apoptosis assays for measuring multiple components on a choice of assay platforms:
- Caspase activity assays
- DNA fragmentation and morphology
- Annexin V staining
- Membrane potential and other mitochondrial assays
Also see flow cytometry assays for apoptosis
|Caspase assays are a distinctive feature of early stage apoptosis.
|DNA fragmentation and nuclear changes characterize late apoptosis.
|Annexin V staining is used to identify intermediate apoptosis stages.
|Mitochondrial changes occur early in apoptosis.
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