Thermo Fisher Scientific offers an array of imaging reagents and kits to detect cells undergoing apoptosis. Select from a wide variety of caspase activity assays, DNA fragmentation and TUNEL assays, annexin V staining reagents and mitochondrial assays.
Accurate apoptosis analysis in your imaging assays
Many different approaches are used in the study of programmed cell death, or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach for accurate assessment. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery. See our range of imaging assays to detect apoptotic cells undergoing processes ranging from caspase activation to phosphatidylserine translocation.
Annexin V staining is used to detect a hallmark of apoptosis, translocation of phosphatidylserine to the outer leaflet of the plasma membrane.
- Alexa Fluor dyes for more sensitive assays
- Multiple conjugates for multiplexing flexibility
- Simple protocol and rapid assays
Activation of caspase enzymes is a distinctive feature of apoptosis.
- Real-time no wash assay for caspase activity
- Multi-parameter assays for live and dead cells
DNA fragmentation and chromatin condensation are observed changes during apoptosis.
- TUNEL assays formatted for imaging and HCS
- DNA stains in ready-to-use format
- Compatible with multiplexed staining procedures
Disruption of mitochondria function is a distinguishing feature of apoptosis.
- Real-time assays in live cells
- Choice of physiological measurements
- Fixable probes for multiplexing with immunodetection
Learn more about
Tools and resources
Apoptosis is the tightly regulated process of controlled cell death in multicellular organisms. Learn more about several of the important pathways.
Apoptosis Information in Cell Analysis Learning Center
Access application notes, webinars and other useful educational resources to help you navigate the complex world of apoptosis research.
For Research Use Only. Not for use in diagnostic procedures.