Review the selection of journal publications and conference posters describing Invitrogen products used in microRNA research. Refer to Invitrogen’s Citations Database for additional references.

Citation Invitrogen Products in Materials and Methods
Josephson, R. et al. Qualification of Embryonic Carcinoma 2102Ep as a Reference for Human Embryonic Stem Cell Research. Stem Cells 2007; 25: 437-446.

This article describes the global and miRNA expression profiles of the embryonal carcinoma line 2102Ep and compares it to hESC lines and alternative reference lines test.
Wang, Y. et al. DGCR8 is Essential for microRNA biogenesis and Silencing of Embryonic Stem Cell Self-Renewal. Nature Genetics 39; 380 - 385.

This article describes the role of miRNAs in ES cell differentiation by generating a Dgcr8 knockout model.
Ryan, DG. et al. MicroRNAs of the Mammalian Eye Display Distinct and Overlapping Tissue Specificity. Molecular Vision 2006; 12: 1175-84.

This article investigated miRNAs tissue and cell-type specificity by expression profiling of low molecular weight RNA isolated from the adult mouse ocular regions.
Landers, M., et. al. NCode MicroRNA Analysis Platform: A Comprehensive Solution for miRNA Profiling. Nature Methods Application Notes 2007.

This application note authored by Invitrogen’s R&D scientists provides an overview of Invitrogen’s miRNA profiling solution.
Goff LA, Rational Probe Optimization and Enhanced Detection Strategy for MicroRNAs Using Microarrays. RNA Biol. 2005 Jul 20;2(3)

This article describes a rational probe design algorithm and a sensitive labeling scheme for optimizing miRNA arrays. It is the article by which the NCode miRNA technology was introduced.
RediPlate™ 96 RiboGreen® RNA Quantitation Kit
Bemis LT,  MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines. Cancer Res.. Mar 2008: 68:1362-1368

This article describes how miR-137 was found to be involved in identification of melanoma susceptibility.
NCode™ First Stand cDNA Synthesis kit
Cameron, JE, et. al. Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling Pathways. J. Virol., Feb 2008; 82; 1946-1958

This article describes how miR-146a was found to be involved in the interferon response pathway.
NCode™ First Stand cDNA Synthesis kit
Takagi S, Post-transcriptional regulation of human pregnane X receptor by microRNA affects the expression of cytochrome P450 3A4. J Biol. Chem., Feb 2008; 10.1074/jbc.M709382200

This article describes how miR-148a was found to post-transcriptionally regulate human PXR.
NCode™ First Stand cDNA Synthesis kit
Wang, Q, miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130. PNAS, Feb 2008; 105:2889-2894

This article describes how an miRNA involved in adipocyte differentiation was found to target Rb2/p130.
Trizol® Reagent 
PureLink™ miRNA Isolation Kit 
NCode™ miRNA Labeling System NCode™ Multi-Species miRNA Microarray V2
Buck, AH, Discrete Clusters of Virus-Encoded MicroRNAs Are Associated with Complementary Strands of the Genome and the 7.2-Kilobase Stable Intron in Murine Cytomegalovirus. J.Virol., Dec 2007; 81; 13761-13770

This article describes how miRNAs involved in murine cytomegalovirus (MCMV) are characterized.
NCode™ SYBR® Green miRNA qRT-PCR Kit
Camps, C. hsa-miR-210 is Induced by  Hypoxia and Is an Independent Prognostic Factor in Breast Cancer. Clin.Cancer, Res., Mar 2008; 14; 1340-1348

This article describes how hypoxia-induced miRNA expression changes may identify markers of survival in breast cancer.
NCode™ miRNA Labeling System
Bahring, S., Inverion Region for Hypertension and Brachydactyly on Chromosome 12p Features Multiple Splicing and Noncoding RNA. Hypertension, Feb 2008; 51; 426-431

This article describes how miRNAs may play a role in autosomal-dominant hypertension and brachydactyly.
NCode™ First Stand cDNA Synthesis kit

Recent Conference Posters

Brooks, et al. NCode™ miRNA Analysis Platform Identifies Differentially Expressed Novel miRNAs in Adenocarcinoma Using Clinical Human Samples Provided By BioServe. Poster presented at the American Association for Cancer Research. San Diego, California, April, 2008.

Wenrich, L. et al. Validating microRNA Targeting of Downregulated Breast Cancer Biomarkers.Poster presented at the American Association for Cancer Research. Los Angeles, California, April, 2007.

Lakshmipathy,U. et al. The NCode miRNA Array: A Rapid and Sensitive Method to Screen Stem Cell Populations. Poster presented at RNAi Conference. Boston, Massachusetts, Dec, 2007.

Hart, R. et al. SP20 microRNA Networks Regulated During Neural Stem Cell Differentiation. Poster presented at the Association of Biomolecular Resource Facilities (ABRF) Annual Conference. Tampa, Florida; March, 2007.

Brooks, M. A Novel Method to Profile miRNA Expression in Different Organisms. Poster presented at the Association of Biomolecular Resource Facilities (ABRF) Annual Conference. Tampa, Florida; March, 2007.

Landers, M. et al. Development of NCode microRNA Direct Labeling Method and Multispecies Array. Poster presented at American Association for Cancer Research. Washington, DC, April, 2006.

Harris, A.N. et al. Exploiting miRNAs for Endogenous Gene Knockdown. Poster presented at the Keystone Symposium on RNAi and Related Pathways. Keystone, Colorado, January, 2006.

More Information

Custom Services

Need help with your miRNA research? Contact us for a consultation and quote today.
Send your questions to our top researchers at