Ion PGM and Ion Proton System Chips | Thermo Fisher Scientific

The Chip is the Machine™

Ion semiconductor sequencing making high-quality next-generation sequencing accessible for all.

The Chip is the Machine™ and Ion Torrent™ directly benefits from four decades of exponential improvement in semiconductor technology. This enables our chips to scale in density for any research application—from small, targeted experiments to large genomes—all on a single platform. See how Ion Torrent Chips work.

With as little as 10 ng input DNA, the new Ion 314™, 316™, and 318™ Chips yield 99.99% consensus accuracy and up to a 50% increase in output over previous chips, in as little as 2 hours on the Ion PGM™ System.

For whole genome sequencing on the Ion Proton™ System, the Ion PI™ Chip enables the highest throughput with up to 10 Gb reads in 2–4 hours.

This unique combination of simplicity and easy scalability makes semiconductor sequencing an accessible next-generation sequencing solution for all researchers, from whole genome/transcriptome to small genome and small RNA sequencing applications.

Compare the data for Ion PGM™ and Ion PI™ Chips, and choose the chip that works best for your sequencing needs:

Ion PGM™ Chip	Run time		Output
	200 bp read	400 bp read	200 bp read	400 bp read
Ion 314™ Chip v2	2.3 hr	3.7 hr	30–50 Mb	60–100 Mb
Ion 316™ Chip v2	3.0 hr	4.9 hr	300–500 Mb	600 Mb–1 Gb
Ion 318™ Chip v2	4.4 hr	7.3 hr	600 Mb–1 Gb	1.2–2 Gb
Ion Proton™ Chip	Run time		Output
	200 bp read		200 bp read
Ion PI™ Chip	2–4 hr		Up to 10 Gb