GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of a-subunits (ai1, ai2 and ai3).
BR; CD49 antigen-like family member B; CD49B; Collagen receptor; GPIa; Integrin alpha-2; ITGA2; Platelet membrane glycoprotein Ia; VLA-2; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
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