Stem Cell Biology Pathways
Browse stem cell biology pathways
Stem cells are undifferentiated cells that can both differentiate into any cell type and can continue to divide indefinitely—otherwise known as self-renewal. There are two broad types of stem cells, embryonic stem cells and adult stem cells, and both are now useful for a wide range of research, engineering, and disease modeling capacities. A number of pathways fall under this area, including the BMP and FGF pathways.
Bone morphogenetic proteins (BMPs) are a large subclass of the transforming growth factor-beta (TGF-beta) superfamily.
One of the most well characterized modulators of angiogenesis is the heparin-binding fibroblast growth factor (FGF).
Hematopoietic stem cells are classified into long-term, short-term, and multipotent progenitors, based on the extent of their self-renewal abilities.
Pluripotent cells are capable of forming virtually all of the possible tissue types found in human beings.
NANOG is a transcription factor transcribed in pluripotent stem cells and is down-regulated upon cell differentiation.
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