Browse stem cell biology pathways

Stem cells are undifferentiated cells that can both differentiate into any cell type and can continue to divide indefinitely—otherwise known as self-renewal. There are two broad types of stem cells, embryonic stem cells and adult stem cells, and both are now useful for a wide range of research, engineering, and disease modeling capacities. A number of pathways fall under this area, including the BMP and FGF pathways.

BMP Pathway

Bone morphogenetic proteins (BMPs) are a large subclass of the transforming growth factor-beta (TGF-beta) superfamily.

FGF Pathway

One of the most well characterized modulators of angiogenesis is the heparin-binding fibroblast growth factor (FGF).

Hematopoiesis from Multipotent Stem Cells

Hematopoietic stem cells are classified into long-term, short-term, and multipotent progenitors, based on the extent of their self-renewal abilities.

Hematopoiesis from Pluripotent Stem Cells

Pluripotent cells are capable of forming virtually all of the possible tissue types found in human beings.

Nanog in Mammalian ESC Pluripotency

NANOG is a transcription factor transcribed in pluripotent stem cells and is down-regulated upon cell differentiation.

Antibodies Resource Library

Access a targeted collection of scientific application notes, methods, and cell signaling charts.