Ion AmpliSeq NGS Panels for Targeted Sequencing
Breakout tools for standout work
Get ultimate flexibility and speed for pivotal results with Ion AmpliSeq panels
When navigating through the complexities of genetic diseases, you need a discovery tool that is both flexible and rapid for analyzing variants of interest. Ion AmpliSeq technology can help.
Ion AmpliSeq technology is globally recognized as the gold-standard, amplicon-based enrichment method for targeted next-generation sequencing (NGS). For the fastest, simplest, and most scalable NGS solution, there is no substitute.
Available in Ready-to-Use, Made-to-Order, and On-Demand formats, Ion AmpliSeq panels consist of a pool of oligonucleotide primer pairs, with each pair designed to amplify a specified genomic region. Each panel can be designed to interrogate all bases across a gene, or it can be focused on specific mutation hotspots.
Gene panels on demand, how and when you want them
Ion AmpliSeq On-Demand panels bring smaller pack sizes and an optimized catalog of pre-tested genes to custom NGS panels, so you can iterate panel design for human disease research with efficiency and convenience.
Not working with human research samples? No problem.
Design a custom panel from 13 predefined genomes, or from your own reference genome after uploading a reference file.
One tube for CNV, SNP, indel, and fusion detection
Simple, versatile technology based on highly multiplexed PCR helps you target tens to hundreds of genes across mutation types including SNPs, indels, fusions, and copy number variants.
What can you do with NGS using Ion AmpliSeq panels? Get results.
After more than 25,000 custom designs and 1000 publications, custom Ion AmpliSeq panels have a track record of superior coverage uniformity, reproducibility, and specificity. They help you get results.
Need even higher sensitivity?
To design your own panels and find variants with a very low limit of detection (down to 0.1%), try Ion AmpliSeq HD technology. This novel library amplification technology enables researchers to get answers when ultrahigh sensitivity is required, such as when detecting low-frequency alleles in circulating tumor DNA or trace pathogenic microbial species in blood.
Ion AmpliSeq panels
Ion AmpliSeq On-Demand panels enable custom panel design in smaller pack sizes from pre-tested genes for practical customization that helps reduce upfront cost and risk.
For maximum flexibility, simply select a subset of targets and enter your specific genomic content online using the Ion AmpliSeq Designer tool, and we will design and create customized Ion AmpliSeq panels just for you. Choose from a number of reference genomes or upload your own reference sequence.
The convenient predesigned Ion AmpliSeq ready-to-use panels allow researchers to focus on data generation and analysis, not on the labor-intensive primer design and target selection steps.
Ion AmpliSeq panels by application
Deafness, epilepsy, cardiac research, and more
Cancer genomics, cancer RNA expression, and more
Tracing the origin of outbreaks, food safety, and more
DNA phenotyping, ancestry, and more
Power and speed for targeted NGS analysis
Ion AmpliSeq panels help you get NGS results from more of your challenging FFPE samples. To do it faster, use the Ion GeneStudio S5 Series sequencers.
Ion AmpliSeq panel results from Boston Children’s Hospital, USA
Applications of targeted NGS panels for clinical research of primary immunodeficiency diseases
Dr. Janet Chou and Wayne Bainter discuss the application of the Ion AmpliSeq Primary Immune Deficiency (PID) Research Panel v2 to accelerate and improve the search for causal variants in clinical research of PIDs.
Videos to help you get started
For Research Use Only. Not for use in diagnostic procedures.