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Protein Dialysis |
Protein dialysis is used to remove small molecules such as salts and detergents from solutions, typically by diffusion through a semi-permeable membrane to improve stability of the protein or enable buffer compatibility with downstream applications. This process allows the protein to be captured while unwanted small molecules pass through the membrane into a surrounding buffer. Find high-quality dialysis products designed to help improve protein purification workflows. Dialysis products include tubing, cups, cassettes, flasks, and plates. The purpose of dialysis in protein purification is to remove small contaminants, which can interfere with protein function and downstream analyses. Explore our selection to find specific dialysis solutions for your research needs.
Dialysis products selection guide
 Dialysis cassettes |  Dialysis flask |  Mini dialysis cups |  Microdialysis plates |  Dialysis tubing | |
|---|---|---|---|---|---|
| External float required? | No | Yes | Yes (0.1 mL size only) | No | No |
| Method of sample addition/removal | Pipette | Pipette, Directly pouring | Pipette | Pipette | Pipette |
| Volume range | 1–125 mL | 150–250 mL | 10 μL–2 mL | 10–100 μL | 10–100 mL |
| Number of devices with different volume capacities | 4–5 | 1 | 3 | 1 | 3 |
| Molecular weight cutoffs (MWCOs) | 2K, 3.5K, 7K (original only), 10K, 20K | 2K, 3.5K, 10K, 20K | 2K (0.1 mL size only), 3.5K, 10K, 20K | 3.5K, 10K | 3.5K, 7K, 10K |
| Automation compatible? | No | No | No | Yes | No |
| Integrated buffer reservoir? | No | No | Yes, except 0.1 mL size | Yes | No |
| Gamma-irradiated options? |
| No | No | No | No |
| Molecular weight cutoff (MWCO) color coded? | Yes | Yes | Yes | No | Yes |
Dialysis tubing
Use dialysis tubing to make dialysis bags traditionally used in protein research labs.
Dialysis cassettes
Dialysis cassettes offer a rigid-framed, free-standing, and self-floating vessel with a secure cap closure and large surface area consisting of regenerated cellulose membranes for simple and efficient dialysis experiments.
Dialysis flasks
Dialysis flasks are excellent for sample volumes ranging from 150–250 mL and the membrane and flask materials are compatible with most laboratory buffers.
Mini dialysis devices
Mini dialysis devices are made of polypropylene and shaped in a cup-like design with integrated, low-binding membranes for convenient, high-performance dialysis of 10 µL to 2 mL samples.
96-well dialysis plates
96-well dialysis plates offer a ready-to-use disposable dialysis solution designed for multiplexing of many small volume samples, 0.1–0.3 mL samples in parallel.
Resources
Learning resources
Support resources
Stylesheet for Classic Wide Template adjustments
For Research Use Only. Not for use in diagnostic procedures.