Manipulating cells for downstream applications
Cellular engineering requires introduction of new genetic content into a cell. One specific type of engineering is reprogramming by conversion of somatic cells into induced pluripotent stem cells. This can be accomplished with Thermo Fisher’s non-integrating technologies by viral delivery or episomal plasmids. Once cell lines have been established, genomic editing and manipulation of iPSCs into other cell types allows for the building of cell models to better answer biological questions.