Chromatography and MS Instruments for Clinical Research & Toxicology

One provider. Extensive capabilities. Achieve success.

Achieve your scientific and business goals for clinical research and toxicology with our extensive, robust, and reliable portfolio of chromatography and mass spectrometry products. From biomarker assays using immunoaffinity enrichment to GC-MS for volatile analysis, and LC-MS for non-volatile compounds, Thermo Fisher Scientific offers an optimal combination of instrumentation, sample preparation, and consumable solutions for endocrinology, clinical translational research, drugs of abuse analysis and therapeutic drug research.

Speak to a specialist  Join our community

On this page


Triple quadrupole MS systems for clinical research & toxicology

Achieve ultimate confidence in your clinical research and toxicology data with our portfolio of triple quadrupoles. Innovations in the ion source, mass analyzer and RF electronics offer high sensitivity, reduced noise, and more data points with high SRM rates. You can confidently quantify compounds at extremely low concentrations, in the most challenging matrices.

TSQ Altis Triple Quadrupole Mass Spectrometer
TSQ Altis Triple Quadrupole Mass Spectrometer
TSQ Quantis Triple Quadrupole Mass Spectrometer
TSQ Quantis Triple Quadrupole Mass Spectrometer
TSQ Fortis Triple Quadrupole Mass Spectrometer
TSQ Fortis Triple Quadrupole Mass Spectrometer
Ultimate sensitivity and selectivity to meet tomorrow's standards today Everyday quantitation workhorse to meet today's standards Quality data across workflows for users at all expertise levels

High resolution, accurate mass Orbitrap Exploris mass spectrometers

Leverage the high resolution, accuracy, and sensitivity of Thermo Scientific Orbitrap mass analyzer technology to address critical challenges faced in quantitation of proteins in complex biological matrices and accelerate your clinical research, translating your qualitative and quantitative assays into future clinical research applications.

Orbitrap Exploris 120 Mass Spectrometer
Orbitrap Exploris 120 Mass Spectrometer
Orbitrap Exploris 240 Mass Spectrometer
Orbitrap Exploris 240 Mass Spectrometer
Orbitrap Exploris 480 Mass Spectrometer
Orbitrap Exploris 480 Mass Spectrometer
Consistent, accurate data, operational simplicity, instrument ruggedness for method development and everyday testing Precision and accuracy to drive discovery, scale up and make an impact, with application versatility and operational simplicity Next-level insights, exploratory and targeted quantitation, next-generation power, performance and ease of use
Need more help choosing an instrument?

Need more help choosing an instrument?

Visit one of the pages below to learn more about the capabilities of our products.


HPLC systems and columns for clinical research & toxicology

Our liquid chromatography (LC) systems feature high sample capacity for high-throughput workflows, industry-leading pumping performance, high S/N and linearity. Our extensive portfolio of HPLC and UHPLC systems can be tailored to provide the best chromatographic resolution for your clinical research assays. We offer binary or quaternary and multichannel systems with a variety of columns, detectors and autosamplers.

  Vanquish Horizon
Vanquish Horizon
 
Transcend Multichannel Systems
Transcend Multichannel Systems
EASY-nLC 1200 System
EASY-nLC 1200 System
 
Flow Range (settable) 0.001–5 mL/min, in 1 µL/min increments 0.001–5 mL/min, in 1 µL/min increments 20–2000 nL/min
Pressure Range 50–1517 bar 50–1517 bar 0 to 1200 bar

HPLC Columns for clinical research & toxicology

Thermo Scientific HPLC Columns are designed to meet a variety of clinical research and toxicology analysis challenges regardless of matrix or analyte.


LC-MS clinical research & toxicology resources

GC-MS systems and columns for clinical research & toxicology

When analytes of interest for clinical research or toxicology are too polar to be retained in an LC separation, or cannot be ionized using electrospray, gas chromatography-mass spectrometry (GC-MS) systems are available for your screening or quantitation assays.

Offers the quantitative power of a GC triple quadrupole MS combined with high-precision, full scan HR/AM capabilities.  

  • Mass range: 50 to 3,000 m/z
  • Detection limit <6 fg OFN
  • Quantitative dynamic range: > 106 
  • Resolving power up to 100,000 at m/z 272
  • Part-per-trillion-level sensitivity

Designed for and developed with high throughput analytical labs to deliver the highest productivity, with MS/MS simplicity and even higher performance SRM.

  • Mass range: 1.2 to 1100 u
  • Detection limit ≤ 0.4 fg OFN depending on configuration
  • Scan up to 20,000 u/s
  • Up to 800 SRM transitions

Gas chromatography columns for clinical research & toxicology

Thermo Scientific GC Columns meet a variety of clinical research and toxicology analysis challenges including monitoring drugs of abuse and blood alcohol levels and performing antidoping analyses.


GC-MS clinical research & toxicology resources

IC-MS systems for clinical research & toxicology

For trace level analysis, our portfolio of ion chromatography systems can be paired with mass spectrometers to provide high resolution, sensitivity, and throughput for even the most complex assays.

We offer a wide variety of chemistries, detectors, and automation options to fit your clinical research and toxicology needs.

Dionex ICS-6000 Hybrid HPIC System

Dionex ICS-6000 Hybrid HPIC System

The Thermo Scientific Dionex ICS-6000 HPIC system enables direct injection with no derivatization and precludes use of organic modifiers in separations.

  • Pressure Range 0 to 35 mPa
  • Flow Rate 0.01 – 10 mL/min
  • Eluent Types: KOH, LiOH, NaOH; Carbonate; Carbonate/Bicarbonate; MSA

ICP-MS systems for clinical research & toxicology

Thermo Scientific ICP-MS platforms enable easy, efficient detection of trace elements in clinical samples.

Whether you perform routine total elemental analyses or state of the art research, this unique system delivers powerful, highly sensitive trace detection, fast. With three models available, the iCAP RQ ICP-MS is the ideal tool for a wide range of applications and market sectors, from routine 24/7 analysis to demanding high quality research.

Increase sample throughput in your laboratory with Thermo Scientific CETAC Autosamplers.

  • CETAC ASX-260 Autosampler offers a 180 sample capacity for low-moderate sample throughput
  • CETAC ASX-520 Autosampler accommodates up to 360 samples for moderate-high sample throughput

HPLC systems and columns for clinical research & toxicology

Our liquid chromatography (LC) systems feature high sample capacity for high-throughput workflows, industry-leading pumping performance, high S/N and linearity. Our extensive portfolio of HPLC and UHPLC systems can be tailored to provide the best chromatographic resolution for your clinical research assays. We offer binary or quaternary and multichannel systems with a variety of columns, detectors and autosamplers.

  Vanquish Horizon
Vanquish Horizon
 
Transcend Multichannel Systems
Transcend Multichannel Systems
EASY-nLC 1200 System
EASY-nLC 1200 System
 
Flow Range (settable) 0.001–5 mL/min, in 1 µL/min increments 0.001–5 mL/min, in 1 µL/min increments 20–2000 nL/min
Pressure Range 50–1517 bar 50–1517 bar 0 to 1200 bar

HPLC Columns for clinical research & toxicology

Thermo Scientific HPLC Columns are designed to meet a variety of clinical research and toxicology analysis challenges regardless of matrix or analyte.


LC-MS clinical research & toxicology resources

GC-MS systems and columns for clinical research & toxicology

When analytes of interest for clinical research or toxicology are too polar to be retained in an LC separation, or cannot be ionized using electrospray, gas chromatography-mass spectrometry (GC-MS) systems are available for your screening or quantitation assays.

Offers the quantitative power of a GC triple quadrupole MS combined with high-precision, full scan HR/AM capabilities.  

  • Mass range: 50 to 3,000 m/z
  • Detection limit <6 fg OFN
  • Quantitative dynamic range: > 106 
  • Resolving power up to 100,000 at m/z 272
  • Part-per-trillion-level sensitivity

Designed for and developed with high throughput analytical labs to deliver the highest productivity, with MS/MS simplicity and even higher performance SRM.

  • Mass range: 1.2 to 1100 u
  • Detection limit ≤ 0.4 fg OFN depending on configuration
  • Scan up to 20,000 u/s
  • Up to 800 SRM transitions

Gas chromatography columns for clinical research & toxicology

Thermo Scientific GC Columns meet a variety of clinical research and toxicology analysis challenges including monitoring drugs of abuse and blood alcohol levels and performing antidoping analyses.


GC-MS clinical research & toxicology resources

IC-MS systems for clinical research & toxicology

For trace level analysis, our portfolio of ion chromatography systems can be paired with mass spectrometers to provide high resolution, sensitivity, and throughput for even the most complex assays.

We offer a wide variety of chemistries, detectors, and automation options to fit your clinical research and toxicology needs.

Dionex ICS-6000 Hybrid HPIC System

Dionex ICS-6000 Hybrid HPIC System

The Thermo Scientific Dionex ICS-6000 HPIC system enables direct injection with no derivatization and precludes use of organic modifiers in separations.

  • Pressure Range 0 to 35 mPa
  • Flow Rate 0.01 – 10 mL/min
  • Eluent Types: KOH, LiOH, NaOH; Carbonate; Carbonate/Bicarbonate; MSA

ICP-MS systems for clinical research & toxicology

Thermo Scientific ICP-MS platforms enable easy, efficient detection of trace elements in clinical samples.

Whether you perform routine total elemental analyses or state of the art research, this unique system delivers powerful, highly sensitive trace detection, fast. With three models available, the iCAP RQ ICP-MS is the ideal tool for a wide range of applications and market sectors, from routine 24/7 analysis to demanding high quality research.

Increase sample throughput in your laboratory with Thermo Scientific CETAC Autosamplers.

  • CETAC ASX-260 Autosampler offers a 180 sample capacity for low-moderate sample throughput
  • CETAC ASX-520 Autosampler accommodates up to 360 samples for moderate-high sample throughput

For General Lab Use Only – Not For Diagnostic Procedures

CMD SchemaApp code