C18 Reversed Phase HPLC Columns

Spoiled for choice

Want a C18 column that's right for your application? Thermo Scientific C18 columns are available with a range of characteristics to provide exceptional performance. These columns are broadly used in a wide variety of applications including pharmaceuticals, steroids, fatty acids, phthalates, environmental and more. They are the most retentive of the alkyl-bonded phases.

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Popular reversed phase C18 HPLC columns
Reversed phase C18 columns

Thermo Scientific Column

Recommended Use

Accucore Vanquish C18+ UHPLC Columns, 1.5µmMeet high throughput demands in your analytical laboratory. This newest innovation in UHPLC columns delivers better, more and easier separations at reduced cost.
Acclaim 120 C18 ColumnsThis high resolution silica column can improve the separation efficiency in your reversed phase applications.
Accucore aQ C18 Polar Endcapped LC ColumnsSeparate polar compounds with improved speed and resolution at low backpressures using the column’s rugged 2.6µm solid-core particles.
Accucore C18 LC ColumnsGet optimal retention of a broad range of nonpolar analytes across multiple applications with a column that has high bonded phase coverage.
Accucore RP-MS LC ColumnsOptimized for MS detection, these clumns are an excellent combination of speed and quality of separation.
Accucore XL C18 LC ColumnsOptimize conventional HPLC methodsof nonpolar analytes. The rugged 4µm solid-core particles ensure very high efficiencies within standard HPLC pressure limits.
Hypersil GOLD aQ C18 Polar Endcapped LC ColumnsRetain and resolve polar analytes. These columns are ideal for use with highly aqueous mobile phases.
Hypersil GOLD C18 Selectivity LC ColumnsAchieve exceptional peak shape and resolution for your HPLC and LC-MS applications with these endcapped, ultrapure, silica-based columns.
Hypersil BDS C18 ColumnsA robust, general-purpose column to use in a wide range of applications.
Hypersil ODS C18 ColumnsA general purpose C18 phase to use for a broad range of applications.
Hypersil ODS-2 C18 ColumnsUse this well-tested, dependable L1 as an alternative to older column brands commonly referenced in validated methods.
Syncronis aQ C18 Polar Endcapped LC ColumnsEnsure consistent, predictable liquid chromatography (LC) separations of polar analytes.
Syncronis C18 ColumnsMaximize reproducibility and laboratory productivity.


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New column technology

Dafydd Milton introduces new Accucore HPLC column technology that enables high-speed, high-resolution separations with backpressures lower than those associated with UHPLC.



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