Automated nucleic acid extraction kits typically include appropriately filled buffers and reagents in vials, cartridges, or plates. The kits are designed to be paired with liquid handlers and purification systems that automate the extraction of DNA and RNA from a variety of biological samples.


What are some of the advantages of magnetic beads over other DNA purification methods?

  • Exceptional binding capacity by thorough exposure to the target during mixing and washing steps
  • Less clogging due to mobile dispersion and regular density
  • Improved elution even at small volumes as a low as 1 mL
  • Greater sample range across samples that have different viscosities
  • Versatility from low to high throughput applications and protocols


Magnetic bead DNA extraction



Magnetic bead RNA extraction

Magnetic bead-based methods of RNA extraction are comparable to other methods, with the added benefits of reduced risk of cross-contamination during sample processing, the ability to isolate RNA directly from a variety of crude sample types, and our magnetic beads are non-porous, removing time-consuming incubation steps.



Cell-free DNA (cfDNA)

Cell-free DNA (cfDNA) can be extracted from multiple sample types using MagMAX Cell-Free Total Nucleic Acid Isolation Kit and MagMAX Cell-Free DNA Isolation Kit. These kits utilize magnetic bead-based technology that helps ensure reproducible recovery of high-quality nucleic acid. This sample preparation step is suitable for a broad range of applications, including real-time PCR, digital PCR, and next-generation sequencing.

Learn more about cell-free DNA (cfDNA) extraction



Formaldehyde-fixed paraffin-embedded (FFPE) tissue sample extraction

Formaldehyde-fixed paraffin-embedded (FFPE) and paraformaldehyde-fixed tissue samples can be sensitive to work with and require attention to detail for proper nucleic acid isolation. Researchers seeking reliable nucleic acid isolation from FFPE samples can achieve this using the MagMAX FFPE DNA/RNA Ultra Kit. DNA and RNA are sequentially extracted from the same FFPE sample in a single workflow, enabling versatile sample analysis. Samples can also be processed either manually or in an automated system using open robotics to process up to 96 samples simultaneously.



Viral and pathogen nucleic acid isolation

MagMAX Viral/Pathogen kits and reagents use magnetic bead-based technology to purify high-quality nucleic acid from a range of research sample types both manually and through automation. To help save time and increase reproducibility, combine with KingFisher instruments for automated purification. Our kits are recommended for viral nucleic acid isolation for SARS-CoV-2 and other infectious disease pathogens.

MagMAX Prime Viral/Pathogen NA Isolation Kit

Recover nucleic acid from viral, bacterial (gram positive and gram negative), fungal, and parasitic pathogens from a variety of biological sample types such as swabs in transport media, saliva, stool, urine, plasma and serum.

Learn More:MagMAX Prime Viral/Pathogen NA Isolation Kit

The following products are recommended for research based viral nucleic acid isolation for SARS-CoV-2 and other infectious disease pathogens. To learn about the differences between the kits, please see Frequently Asked Questions.

For more information on ordering MagMAX Viral/Pathogen II Nucleic Acid Isolation kit (A48383R) please contact customer service.



MagMAX magnetic bead purification by sample type

Microbial DNA isolation

Microbial DNA can be isolated and enriched to help researchers better understand how the microbiome influences human health. It is of utmost importance that the nucleic acids recovered accurately reflect the representation of the diverse microbes in the sample community. Our products offer high- and low-throughput purification of high-quality nucleic acids from a wide variety of sample types, including challenging samples such as stool and soil. Recovered nucleic acids are compatible with a broad range of applications, including microarrays, real-time PCR, and next-generation sequencing.

Viral/Pathogen NA Isolation Kit

Recover mid to high throughput nucleic acid for gastrointestinal testing from biological samples such as stool, urine and saliva.

Learn More:MagMAX Prime Viral/Pathogen NA Isolation Kit

Wastewater testing and surveillance for infectious agents

Wastewater surveillance has recently gained significant attention as a useful tool for monitoring the regional spread of infectious disease, including the novel coronavirus and other airborne pathogens. MagMAX Wastewater Ultra Nucleic Acid Isolation Kits offer a whole host of advantages over traditional wastewater surveillance methods. They are easy to use, and you can isolate nucleic acids from concentrated wastewater in as little as 45 minutes. Our viral enrichment protocol using magnetic beads offers an efficient concentration and nucleic acid isolation.

Explore: Wastewater surveillance

DNA extraction from saliva

Saliva can be collected non-invasively and is a common source of DNA for research. Without compromising yield and purity, the MagMAX Saliva gDNA Isolation Kit uses a single step to minimize the time and effort typically required by other methods which may use multiple laborious sample processing steps. Process a broad range of sample volume inputs simultaneously without sample normalization or reagent volume adjustments for hassle-free sample prep.

Guide for saliva collection and testing

Learn more about saliva-based research in our “How-To” Guide for Saliva Collection and Testing. This complex biofluid plays a critical role in human physiology and disease pathophysiology.

Get your eBook

HIV-1 RNA isolation from dried blood spots

HIV-1 RNA can be isolated now from dried blood spots (DBS), a sample type that requires no specialized equipment for transport and can be shipped at ambient temperatures. DBS sampling is a cost-effective solution, with easy transportation protocols, that can extend the reach of global health and surveillance in remote populations. The MagMAX Viral/Pathogen Nucleic Acid Isolation Kit for HIV-1 Dried Blood Spots isolates and purifies nucleic acid from dried blood spots (DBS) or plasma. The MagMAX Viral/Pathogen Nucleic Acid Isolation Kit for HIV-1 Dried Blood Spots is compatible with KingFisher automated purification systems and downstream assays such as the HIV-1 Genotyping Kit with Integrase.

Genotyping workflow used to detect HIV drug resistance

Steps in a typical genotyping workflow include specimen processing, RNA extraction, RT-PCR, nested PCR, confirmation, purification, cycle sequencing, sequencing clean-up, sequence detection, and data analysis.

Plant cell RNA and DNA extraction

Steps to extract DNA and RNA from plant samples includes the following: Disrupt the tissue and homogenize the plant sample, bind nucleic acid with target magnetic beads, wash and elute sample to purify DNA using a magnetic particle processing instrument or manually using microcentrifuge tubes.

Challenges of extracting DNA and RNA from plants can be difficult and require kits specifically designed to mitigate carbohydrates, phenolics, and other compounds found in plant tissues. Cell walls can be difficult to disrupt, and lysates often contain inhibiting compounds such as tannins, phenolics, and complex polysaccharides which may hinder DNA quality, affecting downstream reactions.

For automated high-throughput extraction or manual purification, the MagMAX Plant DNA Isolation Kit is designed to reduce these challenges and effectively extract DNA from a wide variety of plant species. The kit uses MagMAX magnetic bead technology and eliminates the need for phenol/chloroform extraction or alcohol precipitation. The procedures are optimized for the isolation of DNA from 10–100 mg plant samples. DNA yields vary between different species and tissues depending on genome size, ploidy, cell number, age of tissue sample, and storage conditions.

Microbial DNA isolation

Microbial DNA can be isolated and enriched to help researchers better understand how the microbiome influences human health. It is of utmost importance that the nucleic acids recovered accurately reflect the representation of the diverse microbes in the sample community. Our products offer high- and low-throughput purification of high-quality nucleic acids from a wide variety of sample types, including challenging samples such as stool and soil. Recovered nucleic acids are compatible with a broad range of applications, including microarrays, real-time PCR, and next-generation sequencing.

Viral/Pathogen NA Isolation Kit

Recover mid to high throughput nucleic acid for gastrointestinal testing from biological samples such as stool, urine and saliva.

Learn More:MagMAX Prime Viral/Pathogen NA Isolation Kit

Wastewater testing and surveillance for infectious agents

Wastewater surveillance has recently gained significant attention as a useful tool for monitoring the regional spread of infectious disease, including the novel coronavirus and other airborne pathogens. MagMAX Wastewater Ultra Nucleic Acid Isolation Kits offer a whole host of advantages over traditional wastewater surveillance methods. They are easy to use, and you can isolate nucleic acids from concentrated wastewater in as little as 45 minutes. Our viral enrichment protocol using magnetic beads offers an efficient concentration and nucleic acid isolation.

Explore: Wastewater surveillance

DNA extraction from saliva

Saliva can be collected non-invasively and is a common source of DNA for research. Without compromising yield and purity, the MagMAX Saliva gDNA Isolation Kit uses a single step to minimize the time and effort typically required by other methods which may use multiple laborious sample processing steps. Process a broad range of sample volume inputs simultaneously without sample normalization or reagent volume adjustments for hassle-free sample prep.

Guide for saliva collection and testing

Learn more about saliva-based research in our “How-To” Guide for Saliva Collection and Testing. This complex biofluid plays a critical role in human physiology and disease pathophysiology.

Get your eBook

HIV-1 RNA isolation from dried blood spots

HIV-1 RNA can be isolated now from dried blood spots (DBS), a sample type that requires no specialized equipment for transport and can be shipped at ambient temperatures. DBS sampling is a cost-effective solution, with easy transportation protocols, that can extend the reach of global health and surveillance in remote populations. The MagMAX Viral/Pathogen Nucleic Acid Isolation Kit for HIV-1 Dried Blood Spots isolates and purifies nucleic acid from dried blood spots (DBS) or plasma. The MagMAX Viral/Pathogen Nucleic Acid Isolation Kit for HIV-1 Dried Blood Spots is compatible with KingFisher automated purification systems and downstream assays such as the HIV-1 Genotyping Kit with Integrase.

Genotyping workflow used to detect HIV drug resistance

Steps in a typical genotyping workflow include specimen processing, RNA extraction, RT-PCR, nested PCR, confirmation, purification, cycle sequencing, sequencing clean-up, sequence detection, and data analysis.

Plant cell RNA and DNA extraction

Steps to extract DNA and RNA from plant samples includes the following: Disrupt the tissue and homogenize the plant sample, bind nucleic acid with target magnetic beads, wash and elute sample to purify DNA using a magnetic particle processing instrument or manually using microcentrifuge tubes.

Challenges of extracting DNA and RNA from plants can be difficult and require kits specifically designed to mitigate carbohydrates, phenolics, and other compounds found in plant tissues. Cell walls can be difficult to disrupt, and lysates often contain inhibiting compounds such as tannins, phenolics, and complex polysaccharides which may hinder DNA quality, affecting downstream reactions.

For automated high-throughput extraction or manual purification, the MagMAX Plant DNA Isolation Kit is designed to reduce these challenges and effectively extract DNA from a wide variety of plant species. The kit uses MagMAX magnetic bead technology and eliminates the need for phenol/chloroform extraction or alcohol precipitation. The procedures are optimized for the isolation of DNA from 10–100 mg plant samples. DNA yields vary between different species and tissues depending on genome size, ploidy, cell number, age of tissue sample, and storage conditions.



Automate MagMAX Kits using KingFisher instruments

Four different Kingfisher purification instruments

Benefits of KingFisher instruments include

  • Various throughputs—Process 6–96 samples per run depending on the instrument model
  • Interchangeable formats—Process a wide range of input volumes
  • Protocol customization—Easily edit, modify, or create new protocols
  • Optimized reagents—Compatible with multiple magnetic-bead reagents

Explore: KingFisher instruments
Download: Validated software automation scripts for KingFisher purification instruments

For Research Use Only. Not for use in diagnostic procedures.

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