BioProbes Journal is a biannual publication that highlights a wide range of Thermo Scientific and Invitrogen cell biology products and applications. From new reagents and technologies to product reviews and online tools, we keep you up to date on the latest breakthroughs in cell and protein analysis.
The Current Issue
Recent advances in immuno-oncology (I-O) research are paving the way for the discovery of novel classes of cancer therapeutics that enhance or enable antitumor immune responses, overcome tumor evasion mechanisms, and promote conditions that favor immune protection. Two principal areas of research include the development of biotherapeutic antibodies that target immune-checkpoint pathways and the expansion of cellular approaches such as adoptive cell therapies (ACT). Thermo Fisher Scientific is developing 3D cell culture techniques and low–cell attachment microplates, along with assays and instruments for analyzing cell function. Here we demonstrate the use of several of these techniques and reagents to study immune cell infiltration in 3D tumor spheroid cultures and the subsequent death, by apoptosis, of spheroid cells.
For Research Use Only. Not for use in diagnostic procedures.