Mesenchymal Stem Cell FBS Qualified

Our MSC-Qualified FBS is designed to eliminate the need for you to test multiple FBS lots to identify the optimal one for MSC research. Specially tested to support the expansion and clonal enumeration (by colony forming unit-fibroblast assay) of MSCs

  • Performance-tested using standard 14-day MSC CFU-F assay
  • Each lot is tested against an in-house FBS reference standard using cells from a master cell bank of MSCs from normal bone marrow donors, which helps ensure lot-to-lot consistency

Ideally for researchers studying…*

  • Mesenchymal stem cells
  • Mesenchymal stromal cells
  • Osteogenesis
  • Chondrogenesis and cartilage
  • Collagen and other extracellular matrices (ECM)
  • Adipose tissue and adipogenesis
Bar chart of cloning efficiency for 3 manufacturers of FBS

Figure 1. Effect of FBS source on MSC clonal efficiency (P < 0.05; Student’s t-test). Results from Gibco FBS (2 lots tested are indicated by red and blue bars) are shown along with the results from a competitor's FBS product (yellow bar).

Bar chart of cells per milliliter in culture for 3 manufacturers of FBS

Figure 2. Effect of FBS source on MSC expansion (P < 0.05; Student’s t-test). Results from Gibco FBS (2 lots tested are indicated by red and blue bars) are shown along with the results from a competitor's FBS product (yellow bar).

Ordering information

Publications

  1. Sabrina Viau et.al (2019). A highly standardized and characterized human platelet lysate for efficient and reproducible expansion of human bone marrow mesenchymal stromal cells.
  2. A Srivastava et. al (2018). Secretome of differentiated PC12 cells enhances neuronal differentiation in human mesenchymal stem cells via NGF-like mechanism.
  3. Ganesh Swaminathan et. al (2018). Phenotype-based selection of bone marrow mesenchymal stem cell-derived smooth muscle cells for elastic matrix regenerative in abdominal aortic aneurysms.
  4. Nebiyyeh Kamaci et. al (2011). Selective silencing of DNA Topoisomerase Iiβ in human mesenchymal stem cells by siRNAs (small interfering RNAs)
  5. Thomas G Koch et. al (2009). Improved isolation protocol for Equine cord-blood derived mesenchymal stromal cells.
* These results are based on a review of approximately 10,000 publications using query terms based on the six specialty FBS products offered by Thermo Fisher Scientific. These terms were generated by the MeSH (medical subject headings) taxonomy based on the full text of the paper.

For Research Use Only. Not for use in diagnostic procedures.