High performance

Wide range of sample preparation solutions

Insufficient nucleic acid extraction is the most common cause of molecular workflow issues in commercial supply, so make sure you are using the right products. Bead-based solutions avoid the use of organic solvents or nucleic acid precipitation, helping to eliminate the problems often encountered with filter-based nucleic acid isolation methods.

For your unique assay or application, we offer a wide range of sample preparation solutions, including Invitrogen Dynabeads magnetic beads, which are customizable for your workflow, or turnkey Applied Biosystems MagMAX kits, which are optimized for easy integration. Both Dynabeads and MagMAX kits work seamlessly with Thermo Scientific KingFisher automation instruments for high-throughput genomic analysis. For more unique or demanding applications, our R&D scientists will work closely with you to customize our beads and buffers to your exact specifications.

Take no chances in the effort to achieve your goals. Partner with us for the quality, security of supply, customization, and expertise you can expect from the world leader in serving science.

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Dynabeads magnetic beads

dynabeads-230x195

Dynabeads products offer many unique benefits and are widely used for specific capture and detection of nucleic acids in clinical samples. Some of the products are from our existing bio-discovery portfolio, while others are developed and supplied on an OEM basis. Our beads are monodisperse, with tight CV (coefficient of variation) specifications and exceptional batch-to-batch reproducibility.

In addition to a broad portfolio of off-the-shelf Dynabeads products, our patented technology and proprietary knowledge enable customized product development.

Customization may include: 

  • Coupling of antibody, protein, nucleic acid, or other bioreactive ligands
  • Chemical groups and surface functionality
  • Iron content and magnetic characteristics
  • Bead size, polymer, and pore structure

Dynabeads for nucleic acid purification

CaptureDynabeadsSurfaceBead sizeCharacteristics
GenericMyOne SILANESilica-like1.1 µm
  • Rare or abundant target capture
  • High-efficiency capture 
  • Generic en-masse purification
GenericMyOne Carboxylic AcidHydrophilic

1.1 µm

  • High efficiency capture  
  • Generic en-masse purification
Specific
  •  Oligonucleotide coupling
GenericM-270 Carboxylic AcidHydrophilic2.8 µm
  • High efficiency capture  
  • Generic en-masse purification
Specific
  • Oligonucleotide coupling
SpecificMyOne Streptavidin C1Hydrophilic1.1 µm
  • High surface-to-volume ratio 
  • Fast kinetics 
  • Slow sedimentation
  • Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificMyOne Streptavidin T1Hydrophilic1.1 µm
  • High surface-to-volume ratio 
  • Fast kinetics 
  • Slow sedimentation
  • Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificM-270 StreptavidinHydrophilic2.8 µm
  • Normally low background Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificM-280 StreptavidinHydrophobic2.8 µm

  • Isolation and handling of biotinylated targets
  • Direct or indirect capture of target nucleic acid
  • Use of biotinylated oligos
SpecificOligo(dT)25(M-270)Hydrophilic2.8 µm
  • mRNA (poly A) capture
MagMAX reagents
MagMax kits

MagMAX kits offer a turnkey solution for nucleic acid purification for your application, including pathogen detection and formalin-fixed, paraffin-embedded (FFPE) solid tumor biopsies. The MagMAX solution is an integrated system designed to simplify, standardize, and accelerate preparation of samples derived from various sources for downstream molecular analysis.

MagMAX kits for nucleic acid purification

 Nucleic acid isolatedApplicationFeaturesSample types

MagMAX mirVana 
Total RNA
Isolation Kit

True total RNA (small RNA– enriched total RNA)

RNA-based oncology or infectious disease testing

Works with most samples of interest, including plasma, serum, whole blood, cell culture, tissue, and urine

  • No need to buy multiple kits to work with specific samples 
  • Phenol-free (no organic extraction) 
  • Verified for use with TaqMan® Advanced miRNA Assays

MagMAX DNA 
MultiSample Ultra 2.0 Kit

Genomic DNA

Genotyping for inherited disease, oncology, and infectious disease testing

Compatible with common sample types (whole blood, tissue, saliva, buccal swabs, and oral rinse)

  • Streamlined protocols for numerous noninvasive biological samples

MagMAX Cell-Free DNA Isolation Kit

Cell-free DNA

Noninvasive prenatal testing (NIPT), liquid biopsy

Whole blood

  • Can enrich for cell-free DNA fraction

MagMAX Cell-Free Total Nucleic Acid Isolation Kit

Cell-free DNA
and RNA

NIPT, liquid biopsy

Whole blood

  • Enrichment of all nucleic acid species present in cell-free biological samples such as plasma

MagMAX FFPE DNA/RNA Ultra Kit

DNA and RNA

Genotyping and gene expression for solid tumors

FFPE samples

  • No sample splitting (RNA and DNA from same FFPE section)

MagMAX Pathogen RNA/DNA Kit

RNA and DNA

Infectious disease testing

Serum and plasma; nasal, tracheal, and cloacal swabs; ear samples; whole blood; semen; oral fluid; feces

  • Purification from viruses and easy-to-lyse bacteria and parasites 
  • Low and high sample input volumes

MagMAX Saliva gDNA Isolation Kit

Genomic DNA

A variety of molecular protocols, particularly for direct-toconsumer testing

Saliva

  • Scalable and automatable protocol for the isolation of genomic DNA (gDNA) from fresh and stabilized saliva
KingFisher automation

KingFisher purification systems are designed to deliver high-quality results with minimal hands-on time, helping you automate a significant part of your workflow. KingFisher systems use permanent magnetic rods and disposable tip combs to collect, transfer and mix magnetic particles.

Watch the fully automated, high-throughput KingFisher Presto instrument operating in conjunction with the Hamilton NIMBUS workstation.

KingFisher instruments for nucleic acid purification.

KingFisher Duo PrimeKingFisher FlexKingFisher Presto
  • Semi-automated
  • Fits on the bench
  • 12–24 samples per run
  • Semi-automated
  • 24–96 samples per run
  • Fully automated
  • Integrates with liquid handlers
  • 24–96 samples per run (per instrument)

Dynabeads magnetic beads

dynabeads-230x195

Dynabeads products offer many unique benefits and are widely used for specific capture and detection of nucleic acids in clinical samples. Some of the products are from our existing bio-discovery portfolio, while others are developed and supplied on an OEM basis. Our beads are monodisperse, with tight CV (coefficient of variation) specifications and exceptional batch-to-batch reproducibility.

In addition to a broad portfolio of off-the-shelf Dynabeads products, our patented technology and proprietary knowledge enable customized product development.

Customization may include: 

  • Coupling of antibody, protein, nucleic acid, or other bioreactive ligands
  • Chemical groups and surface functionality
  • Iron content and magnetic characteristics
  • Bead size, polymer, and pore structure

Dynabeads for nucleic acid purification

CaptureDynabeadsSurfaceBead sizeCharacteristics
GenericMyOne SILANESilica-like1.1 µm
  • Rare or abundant target capture
  • High-efficiency capture 
  • Generic en-masse purification
GenericMyOne Carboxylic AcidHydrophilic

1.1 µm

  • High efficiency capture  
  • Generic en-masse purification
Specific
  •  Oligonucleotide coupling
GenericM-270 Carboxylic AcidHydrophilic2.8 µm
  • High efficiency capture  
  • Generic en-masse purification
Specific
  • Oligonucleotide coupling
SpecificMyOne Streptavidin C1Hydrophilic1.1 µm
  • High surface-to-volume ratio 
  • Fast kinetics 
  • Slow sedimentation
  • Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificMyOne Streptavidin T1Hydrophilic1.1 µm
  • High surface-to-volume ratio 
  • Fast kinetics 
  • Slow sedimentation
  • Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificM-270 StreptavidinHydrophilic2.8 µm
  • Normally low background Isolation and handling of biotinylated targets 
  • Direct or indirect capture of target nucleic acid 
  • Use of biotinylated oligos
SpecificM-280 StreptavidinHydrophobic2.8 µm

  • Isolation and handling of biotinylated targets
  • Direct or indirect capture of target nucleic acid
  • Use of biotinylated oligos
SpecificOligo(dT)25(M-270)Hydrophilic2.8 µm
  • mRNA (poly A) capture
MagMAX reagents
MagMax kits

MagMAX kits offer a turnkey solution for nucleic acid purification for your application, including pathogen detection and formalin-fixed, paraffin-embedded (FFPE) solid tumor biopsies. The MagMAX solution is an integrated system designed to simplify, standardize, and accelerate preparation of samples derived from various sources for downstream molecular analysis.

MagMAX kits for nucleic acid purification

 Nucleic acid isolatedApplicationFeaturesSample types

MagMAX mirVana 
Total RNA
Isolation Kit

True total RNA (small RNA– enriched total RNA)

RNA-based oncology or infectious disease testing

Works with most samples of interest, including plasma, serum, whole blood, cell culture, tissue, and urine

  • No need to buy multiple kits to work with specific samples 
  • Phenol-free (no organic extraction) 
  • Verified for use with TaqMan® Advanced miRNA Assays

MagMAX DNA 
MultiSample Ultra 2.0 Kit

Genomic DNA

Genotyping for inherited disease, oncology, and infectious disease testing

Compatible with common sample types (whole blood, tissue, saliva, buccal swabs, and oral rinse)

  • Streamlined protocols for numerous noninvasive biological samples

MagMAX Cell-Free DNA Isolation Kit

Cell-free DNA

Noninvasive prenatal testing (NIPT), liquid biopsy

Whole blood

  • Can enrich for cell-free DNA fraction

MagMAX Cell-Free Total Nucleic Acid Isolation Kit

Cell-free DNA
and RNA

NIPT, liquid biopsy

Whole blood

  • Enrichment of all nucleic acid species present in cell-free biological samples such as plasma

MagMAX FFPE DNA/RNA Ultra Kit

DNA and RNA

Genotyping and gene expression for solid tumors

FFPE samples

  • No sample splitting (RNA and DNA from same FFPE section)

MagMAX Pathogen RNA/DNA Kit

RNA and DNA

Infectious disease testing

Serum and plasma; nasal, tracheal, and cloacal swabs; ear samples; whole blood; semen; oral fluid; feces

  • Purification from viruses and easy-to-lyse bacteria and parasites 
  • Low and high sample input volumes

MagMAX Saliva gDNA Isolation Kit

Genomic DNA

A variety of molecular protocols, particularly for direct-toconsumer testing

Saliva

  • Scalable and automatable protocol for the isolation of genomic DNA (gDNA) from fresh and stabilized saliva
KingFisher automation

KingFisher purification systems are designed to deliver high-quality results with minimal hands-on time, helping you automate a significant part of your workflow. KingFisher systems use permanent magnetic rods and disposable tip combs to collect, transfer and mix magnetic particles.

Watch the fully automated, high-throughput KingFisher Presto instrument operating in conjunction with the Hamilton NIMBUS workstation.

KingFisher instruments for nucleic acid purification.

KingFisher Duo PrimeKingFisher FlexKingFisher Presto
  • Semi-automated
  • Fits on the bench
  • 12–24 samples per run
  • Semi-automated
  • 24–96 samples per run
  • Fully automated
  • Integrates with liquid handlers
  • 24–96 samples per run (per instrument)

For Research Use Only. Not for use in diagnostic procedures.

UX DATA-TRKR Retired - Admins, feel free to remove this reference component.