We have designed medium and high-throughput (HTP) configurations of chemically competent cells, to accommodate your increasing experimental needs. MultiShot Competent Cells are available in three packaging formats, StripWell, FlexPlate, and TOP10 96-well plates offering you flexibility in the number of transformations that can be performed at once for cloning. Choose from one of our convenient product designs.

Which Invitrogen MultiShot product is right for you?


StripWell Chemically
Competent E. Coli

New strains available

FlexPlate Chemically
Competent E. Coli

New configuration

TOP10 Chemically
Competent E. Coli

  • Extremely versatile
  • Perform 1 to 96 transformations
  • Very adaptable
  • Use as multiples of
    8-wells up to an entire plate
  • A high throughput tool ideal for automation
Format12 x 8-tube strips96-well PCR plate that can be separated into
12 x 8-well segments
96-well plates 

Kit size

1 rack (12 x 8-tube strips)1 segmented plate5 plates

Volume per well

50 μL20 μL15 μL

Video: Invitrogen MultiShot high-throughput chemically competent E. coli product overview

Transformation Efficiencies of DH5α Competent E. coli and DH5α derivatives

Comparing DH5α competent E. coli and 5α derivatives in multiple product configurations

Figure 1. Comparing DH5α competent E. coli and 5α derivatives in multiple product configurations. Transformation efficiency was measured by performing triplicate transformations, using 10 pg pUC19 DNA, per manufacturer’s recommended protocol. Each transformation was plated in duplicate.

Find the MultiShot strain and format that you need

We also offer many other different strains and formats of chemically competent cells and electrocompetent cells to help meet your specific transformation needs. If you require other high-throughput transformation options contact us for custom formatting options.

Ordering information


Competent cells resources

Have any questions on competent cells or transformation? Click below to access overviews, videos, genotype guides and educational resources.

Cloning Support Center

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cloning applications

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