Delivering a new level of performance, reproducibility, and accuracy of results

Introducing our modernized Thermo Scientific SureSTART collection of vials and caps.

Because experiments, analytes, or budgets are different, we’ve organized SureSTART vials and closures into three performance levels to provide you with the affordability, compatibility and performance you need.

  • Performance Level 1: Everyday applications; choose these for the cost-effective choice
  • Performance Level 2: High throughput applications; choose these when robustness and reproducibility are key
  • Performance Level 3: High performance; choose these when sensitivity is a must

No HPLC/UHPLC or GC instrument has been left behind. Our vials and well plates are suitable for all vendors' instruments. All SureSTART products are Specification Certified. In addition, kits are either LC/GC Certified or MS Certified.

Get a sure start with these SureSTART products to obtain the performance, reproducibility, and accuracy of results you’re looking for. See how this vials and closures collection delivers a first-class product experience from purchase to final result. 

Looking for an autosampler well plate? See our comprehensive range of Chromatography Autosampler Well Plates for high-density sample handling in chromatography.

 

SureSTART vials & cap closures benefits

Assured quality & performanceInstrument
compatibility
Sample
security
Low compound adsorptionBetter product experienceExercise your
budget power
  • Stringent quality checks
  • Right products for your applications & regulatory requirements
  • Innovation for higher performance
  • Precise & consistent measurement of challenging analytes
  • Compatibility with add-on and integrated autosamplers
  • Supports all chromatography and MS instruments
  • Vial, caps, septa, inserts, kits; well plates and mats
  • price and performance level to fit your needs
  • Keep samples safe and secure
  • Technology prevents analyte loss from cap closure
  • Quality materials reduces background & shifting retention times
  • GOLD-Grade vials prevent analyte adsorption, pH shifting, adducting, or contamination
  • Three performance levels
  • Level identified by “waves” on vials
  • All products Specification Certified
  • Kits LC/GC Certified, or MS Certified
  • Choice of performance levels
  • Buy in bulk and save
Level 1 — SureSTART Vials & Cap Closures for General Purpose Applications

 

If you are verifying compound presence and performing quantification using detection techniques such as UV, RI and FID, our Performance Level 1 products are the perfect solution for you – select the products with the one wave.

Level 1 – vials & cap closures

Level 2 — SureSTART Vials & Cap Closures for High Throughput Applications

Get the performance you need to deliver high quality data with an uninterrupted workflow.

Our Performance Level 2 range has very low metal content and extractables and leachables, so that you have the assurance that each product conforms to the same high standards you are working with to meet to your regulatory requirements.

If you need products that support routine analyses, our Performance Level 2 products are here for you. Select the products with two waves.

Level 2 - vials & cap closures

Level 2 - headspace vials & cap closures

Level 2 - vial, cap, and septa kits

SureSTART Certified
2 mL Screw Vial & Cap Kits
SureSTART Certified
EPA Screw Vial & Cap Kits
SureSTART Certified
Scintillation Screw Vial & Cap Kits
Level 2 SureSTART Certified 2 mL Screw Vial & Cap KitsLevel 2 SureSTART Certified EPA Screw Vial & Cap KitsLevel 2 SureSTART Certified Scintillation Screw Vial & Cap Kits
Standard 2 mL screw top vial-cap kits; including
SureStop vials with AVCS caps
4, 8, 12, 16, 20, or 40 mL vial-cap kits20 mL screw top vials with 24 mm caps  
Innovative technology ensures proper vial-cap seal every timeFor use with environmental analyses under EPA regulationsFor use with scintillation assays  
Tested & certified:
For 15 critical physical specifications
Tested & certified:
For 15 critical physical specifications
To ensure no residual manufacturing agents
Tested & certified:
For 15 critical physical specifications
Level 3 — SureSTART Vials & Cap Closures for High Performance Applications

Protect your most valuable samples and deliver consistent, reproducible results for your most demanding analyses.

Our SureSTART Performance Level 3 products are packed in clean rooms to protect them against environmental factors, and contain the lowest amounts/levels of metals, extractables, and leachables; ensuring that you can get the sensitivity and selectivity from your most challenging analytes confidently and consistently.

If you are looking for the ultimate performance from your methods while maintaining the highest levels of sample security and integrity, our Performance Level 3 products will meet your needs. Select the products with three waves.

Level 3 - microvials for < 2 mL samples

3 - vial, cap, and septa kits

SureSTART HPLC & GC Certified
Screw Vial & Cap Kits

SureSTART MSCERT
Screw Vial & Cap Kits
SureSTART MSCERT+
Screw Vial & Cap Kits
SureSTART Certified TOC Screw Vial & Cap KitsSureSTART Certified
Screw Vial & Cap Kits

Level 2 SureSTART Certified 2 mL Screw Vial & Cap KitsLevel 3 SureSTART MSCERT Screw Vial & Cap KitsLevel 3 SureSTART MSCERT+ Screw Vial & Cap KitsLevel 3 SureSTART Certified TOC Screw Vial & Cap KitsLevel 3 SureSTART Certified Screw Vial & Cap Kits
Certified 2 mL screw top vial-cap kits; includes SureStop vials with AVCS capsCertified 2 mL screw top vial-cap kits; includes SureStop vials with AVCS capsCertified 0.2, 1.5, and 2 mL screw top vial-cap kits; includes SureStop vials with AVCS caps; precleaned vialsCertified 40 mL screw top vials with 24 mm cap closures0.2 and 2 mL screw top vial-cap kits; includes SureStop vials with AVCS caps
Includes innovative vial-cap technology to ensures proper screw cap seal every time
Highest levels of sample security and integrity
Use with mass spectrometry
Low adsorption
Direct injection analysis (DIA)
Innovative vial-cap technology
Highest levels of sample security and integrity
Use with mass spectrometry
Low adsorption
Direct injection analysis (DIA)
Innovative vial-cap technology
Highest levels of sample security and integrity
For use in total organic carbon analysesIncludes innovative vial-cap technology to ensure proper screw cap seal every time
Tested & certified:
For 15 critical physical specifications
To ensure no residual manufacturing agents
Tested & certified:
For 15 critical physical specifications
To ensure no residual manufacturing agents
Precleaned. Tested & certified:
For 15 critical physical specifications
To ensure no residual manufacturing agents
Tested & certified:
For 15 critical physical specifications
For total organic carbon levels <10 or <20 ppb
Tested & certified:
For 15 critical physical specifications
Certificate provided with each kit

 
 
Featured videos

One collection. Three performance levels. All from one trusted source.

 

SureSTART – Five reasons why
 

 

All about microvials
 

 

See how SureStop vials with AVCS caps Work

 

Thermo Scientific SureSTART vial inserts

 

 
 
 
SureSTART vials & closures Q&A

The SureSTART portfolio is a comprehensive list of vials, caps, inserts, well plates, mats and accessories that are suitable for use with chromatographic workflows. The SureSTART portfolio contains three different performance levels that have been quality checked to provide a robust and reliable product.

The SureSTART portfolio includes products that could previously been found in our legacy brands such as National Scientific, Chromacol, and Sun-Sri.

Many of the products that were branded as National Scientific and Chromacol have been absorbed into the new Thermo Scientific SureSTART Collection, although there are still a few products that still exist within the marketplace.

For more information please contact your local sales representative or complete the Inquiries form on this page.

All glass vials found within the three different performance levels are made from Type 1 Class A Borosilicate glass. This type of glass has excellent chemical resistance properties that make it ideal for the containment or storage of acidic, neutral and alkaline samples/analytes. The vials also have high temperature resistance and are suitable for use in temperatures between -50°C to 120°C (although a rapid change in temperature of the products should be avoided). 

The Performance Level 1 vials are designed to identify those which are suitable for simple routine, testing with limited budget. Glass vials have a single wavy line.

For most analytical requirements the Performance Level 2 products will be suitable for use with higher sensitivity methods while maintaining throughput. Glass vials have two wavy lines.

For the most stringent analytical requirements the Performance Level 3 products have advanced features which make them suitable for use with difficult samples in terms of chemistry and available sample volume. All products are made from 33-expansion glass and these vials have three wavy lines.

These are vials are suitable for use when sample volume is limited or when you need to get maximum recovery from the vial. These vials allow small volumes to be sampled accurately by autosamplers with a recoverable volume of much less than 100 µL. High recovery, total recovery and vials with fixed inserts are all classed as microvials.

The micro inserts have a small total volume capacity of <400uL and can be classified as either Polyspring, conical, or flat bottom within the SureSTART Collection. Micro inserts are placed and sealed inside a vial so they can be used in conventional autosampler racks. The smaller 6 mm diameter of the insert gives better sample recovery than a routine flat based vial; with conical inserts being most effective with residual volumes of 1-2 microliters. Many are held in place by a Polyspring, which cushions and centers the insert.

During manufacture the outer vial has a glass micro-insert precisely positioned inside and this is permanently fused to the base of the outer vial. This gives a 12 mm x 32 mm microvial with a capacity of 350 microliters with a narrow reservoir with <10ul capacity. Removes the need to assemble a vial and insert prior to use.

These one-piece microvials have a very low residual volume due to a specially shaped deep and narrow inner reservoir which collects the liquid in the base so compatible autosamplers can collect all but 1-2 microliters of sample while having a total sample volume of 1.2mL. The outer dimension for these vials is 12x32mm.

These one-piece microvials have an internal conical reservoir which collects liquid in a 30uL volume for extraction with a conventional autosampler from a total usable volume of 1.7 mL. The outer dimension for these vials is 12x32 mm.

In addition to the features on standard 2 mL vials, SureStop vials also have a patented definite stop point (alignment ring) in the design of the vial finish. This prevents the vial from being an optimal seal which eliminates under- and over-sealing by the cap/closure, and user-to-user variance.

SureStop vials are designed for use with AVCS system screw caps. They improve transfer reliability and give a more secure liquid seal than standard screw vials. SureStop vials are available as a 2 mL as either clear or amber options and are highly recommended for use with GC and LC applications.

Thermo Scientific Advanced Vial Closure System (AVCS) caps are polypropylene caps that are compatible with all 9 mm short thread screw vials, although we recommend that they are used with our Thermo Scientific SureStop vials to get maximum benefit of the two technologies. There is a leveling feature within the AVCS designed caps that provide optimal liquid sealing. The innovative features found on the AVCS cap also give more autosampler compatibility with less autosampler interruptions, as a result of misaligned cap tilting, dislodged septa or septa push through.

AVCS caps not only have the most effective seal but they also contain significantly less leachables than bonded caps. You’ll see a noticeably cleaner spectra when you use SureStop and AVCS as an alternative to bonded caps. The AVCS caps also come with a range of different septa materials.

For analysis of compounds which show interactions with untreated glass surfaces it may be necessary to use a deactivated glass vial. The effect of adsorption is most apparent when dealing with very low concentrations of the sample. It is likely that this effect will only be identified during calibration. Analytical results will show poor reproducibility and linearity for active samples while non-adsorbing species show good results.

Inert glass products can be found in Performance level 3 and include silanized glass and GOLD-grade technology deactivated glass.

For very polar compounds including ionizable biomolecules and inorganic ions the use of a plastic vial may be considered. Polypropylene vials are included in the SureSTART range as a Level 1 range of products.

Most polar analytes can be analyzed successfully in glass vials with few problems at normal analytical levels. Low concentrations may require investigation of deactivated vials but in most cases the control of the sample pH is enough to maintain linearity.

Type 1 neutral borosilicate glass is suitable for neutral/acid samples with little change of pH caused by the glass surface.

GC: Vials are most applicable with GC methods with longer run-times. The glass vials are more compatible with the strong organic solvents used to solubilize liquid samples.

HPLC: When processing samples in batches of less than 50 use vials as there is little advantage using a 96-well plate as the plate capacity would not be fully utilized.

HPLC/UHPLC: Plates are most useful when utilizing a high sample throughput for sample preparation with automated sample handling.

They must also be utilized with short run times to give the required throughput.

Use with multi-plate stackers to give maximum sample capacity.

BioLC/NanoLC: When using very small samples it may be more convenient to use plastic or glass microvials. The sample is secure and maximum recovery of the sample from the narrow inserts is possible.

Headspace vials are used when you want to analyse the gaseous phase of the sample rather than the liquid phase. These vials have a thicker glass wall to withstand higher temperature and internal pressure for the analysis of volatile gas in the vial’s headspace. Headspace vials with 20 mm crimp tops and 18 mm screw tops in sizes ranging from 6 mL to 20 mL are available in clear or amber glass. Choose from a round or flat base with a beveled or square edge finish.

  • Round base vials are compatible with most autosamplers and are more easily handled by robotic arms that lift the vial from the tray.
  • Flat base vials maximize heating efficiency in manual headspace sampling and are required for use in some instrument models.
  • The bevel edge on a vial lip provides additional sealing power for greater leak resistance under high pressure.

 

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