No-Fail SureStop Screw Vials & AVCS Caps

An optimal screw top seal every time

Prevent screw thread vial failures such as cap tilt, cap deformities, dislodged septa or septum push through. Thermo Scientific SureStop Vials and Advanced Vial Closure System (AVCS) caps are specially designed to:

  • Properly seal every time
  • Significantly reduce re-analysis
  • Increase sample throughput
  • Reduce solvent/sample evaporation
  • Maintain sample/data integrity
  • Provide an alternative to crimp, snap, and bonded caps
  • Works with both LC and GC instruments

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Thermo Scientific SureStop screw thread vials, AVCS caps, and kits

SureStop vials are designed as part of the Advance Vial Closure System (AVCS) and remove any subjectivity around achieving the optimal seal compression when closing a vial. Below are 2mL, 12x32mm vials in clear and amber glass with 9mm screw thread vials for use with AVCS caps to provide the ultimate in sample security

9mm SureStop Screw Top Vials
Catalog Glass Marking spot Dimensions Base Volume (total) Vol (useable) Vol (residual) Pack of
C5000-1 Clear No 12x32 Flat 2.0mL 1.5mL <170 100
C5000-1W Clear Yes 12x32 Flat 2.0mL 1.5mL <170 100
C5000-2 Amber No 12x32 Flat 2.0mL 1.5mL <170 100
C5000-2W Amber Yes 12x32 Flat 2.0mL 1.5mL <170 100
2-SVWGK Clear
Gold
Grade
Yes 12x32 Flat 2.0mL 1.5mL <170 100
2-SVWK(A) Amber Yes 12x32 Flat 2.0mL 1.5mL <170 100

The 9mm AVCS closures (C5000- and K-series) complement SureStop vials and are based on Thermo Scientific Advance Vial Closure System (AVCS), designed to overcome challenges associated with 9mm closures. It features a completely redesigned septa/cap interface that is designed to virtually eliminate septa push-through while improving sealing. Thermo Scientific in-house testing has also shown reduced evaporation compared to all other 9mm closures. In addition, the increased surface area available for injection provides compatibility with a broader range of autosamplers than previous designs.

As with any vial cap, choose the preferred cap color (black, blue, red, green, yellow, pink, white, grey, or transparent) paired with the septum that is compatible with your autosampler needle (gauge and tip form) and solvent. The softer the septum, the thinner the needle can be. Sealing and re-sealing is improved by softer septa. Harder septa have no “trampoline” effect and a sharp needle can easily penetrate the septa with little resistance.

9 mm AVCS Caps and Septum Combination Seals

Catalog Cap color Cap material Septum Hardness Thickness Pack of
9mm AVCS Open Top Screw Cap, 6mm hole
C5000-44B Blue Polypropylene Soft septum, PTFE/Blue Silicone 30 1.0 100
C5000-45B Blue Polypropylene Soft septum, PTFE/Blue Silicone, Pre-slit 30 1.0 100
9-SCK(B)-ST101 Blue Polypropylene Blue Silicone/PTFE 30 1.0 500
C5000-51 Red Polypropylene Ivory PTFE/Red Rubber 45 1.0 100
C5000-51Y Yellow Polypropylene Ivory PTFE/Red Rubber 45 1.0 100
C5000-51P Pink Polypropylene Ivory PTFE/Red Rubber 45 1.0 100
C5000-57B Blue Polypropylene Ivory PTFE/Red Rubber, Pre-slit 45 1.0 100
C5000-57G Green Polypropylene Ivory PTFE/Red Rubber, Pre-slit 45 1.0 100
C5000-64B Black Polypropylene Bonded Red PTFE/White Silicone 45 1.0 100
C5000-75C Gray Polypropylene Bonded Red PTFE/White Silicone, Pre-slit 45 1.0 100
C5000-62B Blue Polypropylene Bonded Natural PTFE/Clear Silicone 45 1.3 100
C5000-53A Black Polypropylene Red PTFE/White Silicone/Red PTFE 50 1.0 100
C5000-53B Blue Polypropylene Red PTFE/White Silicone/Red PTFE 50 1.0 100
C5000-53G Green Polypropylene Red PTFE/White Silicone/Red PTFE 50 1.0 100
C5000-53R Red Polypropylene Red PTFE/White Silicone/Red PTFE 50 1.0 100
C5000-53Y Yellow Polypropylene Red PTFE/White Silicone/Red PTFE 50 1.0 100
C5000-54A Black Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-54B Blue Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-54G Green Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-54R Red Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-54Y Yellow Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-54P Pink Polypropylene Red PTFE/White Silicone 55 1.0 100
C5000-55A Blue PTFE/White Silicone, Pre-slit Polypropylene Black 55 1.0 100
C5000-55B Blue Polypropylene Blue PTFE/White Silicone, Pre-slit 55 1.0 100
C5000-55G Green Polypropylene Blue PTFE/White Silicone, Pre-slit 55 1.0 100
C5000-55R Red Polypropylene Blue PTFE/White Silicone, Pre-slit 55 1.0 100
C5000-55Y Yellow Polypropylene Blue PTFE/White Silicone, Pre-slit 55 1.0 100
C5000-55P Pink Polypropylene Blue PTFE/White Silicone, Pre-slit 55 1.0 100
C5000-52AE Blue Polypropylene Solid PTFE Disk with Silicone sealing ring 53 1.0 100
9-SCK(B)-ST1 Blue Polypropylene White Silicone/Red PTFE 57 1.0 500
9-SCK(G)-ST1 Green Polypropylene White Silicone/Red PTFE 57 1.0 500
9-SCK(N)-ST1 Clear Polypropylene White Silicone/Red PTFE 57 1.0 500
9-SCK(B)-ST1X Blue Polypropylene White Silicone/Red PTFE, Y-Pre-slit 57 1.0 500
9-SCK(B)-TST1 Blue Polypropylene Red PTFE/White Silicone/Red PTFE 57 1.0 500
9-SCK(B)-8RT1 Blue Polypropylene Red Rubber/Clear PTFE 58 1.0 500
9-SCK(B)-8RT1X Blue Polypropylene Red Rubber/Clear PTFE, Pre-slit 58 1.0 500
C5000-56AL Blue Polypropylene Solid Aluminum Disk with Silicone sealing ring - 0.06 100
9mm AVCS Screw Cap with Integral PP Membrane
C5000-50 Clear Polypropylene Polypropylene N/A N/A 100
C5000-50B Blue Polypropylene Polypropylene N/A N/A 100
9-SCNKB Blue Polypropylene Polypropylene     500
9mm AVCS Closed Top Screw Top Cap
C5000-99B Blue Polypropylene Ivory PTFE/Red Rubber 45 1.0 100
9mm AVCS Magnetic Open Screw Top Cap, 6mm hole
C5000-46M Blue Polypropylene Soft septum, PTFE/Blue Silicone 30 1.0 100
C5000-47M Blue Polypropylene Soft septum, PTFE/Blue Silicone, Pre-slit 30 1.0 100
9-MSC(BG)-ST1 Blue/Gold PP/Steel Soft septum, PTFE/Blue Silicone, Pre-slit 30 1.0 100
9-MSC(BG)-ST1 Blue/Gold PP/Steel White Silicone/Red PTFE 57 1.0 100
9-MSC(BG)-ST101 Blue/Gold PP/Steel Soft septum, Blue Silicone/PTFE 30 1.0 100
9-MSC(BG)-ST101X Blue/Gold PP/Steel Soft septum, Blue Silicone/PTFE, Pre-slit 30 1.0 100

9mm Wide Opening Screw Thread Vials Convenience Kits

Kit Catalog Glass Patch Cap Septum Vial Catalog /
Closure Catalog
Pack of
Unassembled Kits – SureStop vials with AVCS caps
C5000-580 Clear No Blue Ivory PTFE/Red Rubber C5000-1
C5000-51B
100
C5000-580W Clear Yes Blue Ivory PTFE/Red Rubber C5000-1W
C5000-51B
100
C5000-592 Clear No Blue Red PTFE/White Silicone C5000-1
C5000-54B
100
C5000-592W Clear Yes Blue Red PTFE/White Silicone C5000-1W
C5000-54B
100
C5000-586W Clear Yes Blue Red PTFE/White Silicone/Red PTFE C5000-1W
C5000-53B
100
C5000-595W Clear Yes Blue Blue PTFE/White Silicone, Pre-slit C5000-1W
C5000-55B
100
2-SVWGK8-CPK Clear GOLD GRADE Yes Blue Red Natural Rubber/Clear PTFE 2-SVWGK
9-SCK(B)-8RT1
100
2-SVWGKST-CPK Clear GOLD GRADE Yes Blue White Silicone/Red PTFE 2-SVWGK
9-SCK(B)-ST1
100
2-SVWK(A)8-CPK Amber Yes Blue Red Natural Rubber/Clear PTFE 2-SVWK(A)
9-SCK(B)-8RT1
100
2-SVWK(A)8-CPK Amber Yes Blue Red Natural Rubber/Clear PTFE 2-SVWK(A)
9-SCK(B)-8RT1
100
2-SVWK(A)ST-CPK Amber Yes Blue White Silicone/Red PTFE 2-SVWK(A)
9-SCK(B)-ST1
100
Unassembled Kits – Standard vials with AVCS caps
C5000-80 Clear No Blue Ivory PTFE/Red Rubber C4000-1
C5000-51B
100
C5000-80W Clear Yes Blue Ivory PTFE/Red Rubber C4000-1W
C5000-51B
100
C5000-82P Amber Yes Pink Ivory PTFE/Red Rubber C4000-2W
C5000-51P
100
C5000-82W Amber Yes Blue Ivory PTFE/Red Rubber C4000-2W
C5000-51B
100
C5000-83W Clear Yes Blue Ivory PTFE/Red Rubber, Pre-slit C4000-1W
C5000-57B
100
C5000-86 Clear No Blue Red PTFE/White Silicone/Red PTFE C4000-1
C5000-53B
100
C5000-86W Clear Yes Blue Red PTFE/White Silicone/Red PTFE C4000-1W
C5000-53B
100
C5000-88W Amber Yes Blue Red PTFE/White Silicone/Red PTFE C4000-2W
C5000-53B
100
C5000-87 Polypropylene No Blue Red PTFE/White Silicone C4000-11
C5000-54B
100
C5000-91W Clear Yes Black Red PTFE/White Silicone C4000-1W
C5000-54A
100
C5000-92 Clear No Blue Red PTFE/White Silicone C4000-1
C5000-54B
100
C5000-92P Clear No Pink Red PTFE/White Silicone C4000-1
C5000-54P
100
C5000-92W Clear Yes Blue Red PTFE/White Silicone C4000-1W
C5000-54B
100
C5000-94W Amber Yes Blue Red PTFE/White Silicone C4000-2W
C5000-54B
100
C5000-95 Clear No Blue Blue PTFE/White Silicone, Pre-slit C4000-1
C5000-55B
100
C5000-95W Clear Yes Blue Blue PTFE/White Silicone, Pre-slit C4000-1W
C5000-55B
100
C5000-LV95 Clear No Blue Blue PTFE/White Silicone, Pre-slit C4000-LV1
C5000-55B
100
C5000-97 Polypropylene No Blue Blue PTFE/White Silicone, Pre-slit C4000-11
C5000-55B
100
C5000-78W Clear Yes Black Bonded Red PTFE/White Silicone C4000-1W
C5000-64B
100
C5000-93W Clear Yes Gray Bonded Red PTFE/White Silicone, Pre-slit C4000-1W
C5000-75C
100
C5000-80WY Clear Yes Yellow Ivory PTFE/Red Rubber C4000-1W
C5000-51Y
100
C5000-92WY Clear Yes Yellow Yellow PTFE/White Silicone C4000-1W
C5000-54YY
100
C5000-86WY Clear Yes Yellow Yellow PTFE/White Silicone/Yellow PTFE C4000-1W
C5000-53YY
100
C5000-94WY Amber Yes Yellow Yellow PTFE/White Silicone C4000-2W
C5000-54YY
100
2-SVW8-CPK Clear Yes Blue Red Natural Rubber/Clear PTFE 2-SVW
9-SCK(B)-8RT1
100
2-SVWST-CPK Clear Yes Blue White Silicone/Red PTFE 2-SVW
9-SCK(B)-ST1
100
2-SVW(A)8-CPK Amber Yes Blue Red Natural Rubber/Clear PTFE 2-SVW(A)
9-SCK(B)-8RT1
100
2-SVW(A)ST-CPK Amber Yes Blue White Silicone/Red PTFE 2-SVW(A)
9-SCK(B)-ST1
100
Assembled Kits – Standard vials with AVCS caps
C5000-180 Clear No Blue Ivory PTFE/Red Rubber C4000-1
C5000-51B
100
C5000-180W Clear Yes Blue Ivory PTFE/Red Rubber C4000-1W
C5000-51B
100
C5000-182W Amber Yes Blue Ivory PTFE/Red Rubber C4000-2W
C5000-51B
100
C5000-183W Clear Yes Blue Ivory PTFE/Red Rubber, Pre-slit C4000-1W
C5000-57B
100
C5000-184W Amber Yes Blue Ivory PTFE/Red Rubber, Pre-slit C4000-2W
C5000-57B
100
C5000-186 Clear No Blue Red PTFE/White Silicone/Red PTFE C4000-1
C5000-53B
100
C5000-186W Clear Yes Blue Red PTFE/White Silicone/Red PTFE C4000-1W
C5000-53B
100
C5000-186WR Clear Yes Red Red PTFE/White Silicone/Red PTFE C4000-1W
C5000-53R
100
C5000-188W Amber Yes Blue Red PTFE/White Silicone/Red PTFE C4000-2W
C5000-53B
100
C5000-186WY Clear Yes Yellow Yellow PTFE/White Silicone/Yellow PTFE C4000-1W
C5000-53YY
100
C5000-192 Clear No Blue Red PTFE/White Silicone C4000-1
C5000-54B
100
C5000-192W Clear Yes Blue Red PTFE/White Silicone C4000-1W
C5000-54B
100
C5000-194W Amber Yes Blue Red PTFE/White Silicone C4000-2W
C5000-54B
100
C5000-195W Clear Yes Blue Blue PTFE/White Silicone, Pre-slit C4000-1W
C5000-55B
100
C5000-196W Amber Yes Blue Blue PTFE/White Silicone, Pre-slit C4000-2W
C5000-55B
100

We offer the most suitable combination packs for the most popular instruments currently in use. The contents have been carefully chosen to match the needs of particular autosamplers.

Instrument-Specific Kits with Surestop vials and/or AVCS caps
Kit Designed for Catalog Glass Patch Cap Septum Vial Catalog / Closure Catalog Pack of
Instrument-Specific Unassembled Convenience Kits with SureStop vials and AVCS caps
Thermo GC Autosampler TTRGKK Clear GOLD Grade Yes Blue Blue Silicone/PTFE 2-SVWGK
9-SCK(B)-ST101
100
Instrument-Specific Unassembled Convenience Kits with standard vials and AVCS caps
Agilent LC Autosampler HPLSK Clear Yes Blue Red Natural Rubber/Clear PTFE 2-SVW
9-SCK(B)-8RT1
100
Thermo GC Autosampler TTRK Clear Yes Blue Blue Silicone/PTFE 2-SVW
9-SCK(B)-ST101
100
Varian GC Autosampler (Assembled) VAGK Clear Yes Blue White Silicone/Red PTFE 2-SVW
9-SCK(B)-ST1
100
Varian LC Autosampler VALK Clear Yes Blue White Silicone/Red PTFE 2-SVW
9-SCK(B)-ST1
100
Waters Alliance® LC Autosampler WALK Clear Yes Blue White Silicone/Red PTFE 2-SVW
9-SCK(B)-ST1
100
PerkinElmer LC Autosampler PELK Clear Yes Green White Silicone/Red PTFE, Preslit 2-SVW
9-SCK(G)-ST1X
100
Waters Alliance LC Autosampler WALBK Clear Yes Black Bonded Red PTFE/White Silicone 2-SVW
9-SCK(BLK)-BST1
100
National 9mm Wide Opening Screw Thread Vial Storerooms
Kit Catalog Glass Patch Cap Septum Vial Catalog / Closure Catalog Pack of
9 Drawer Storeroom, 2000 pieces, SureStop vials with ACVS Caps
C5075-213 Clear Yes Blue Red PTFE/White Silicone/Red PTFE C5000-1W
C5000-53B 
1
C5075-219 Clear No Blue Red PTFE/White Silicone C5000-1
C5000-54B 
1

Certifications become more and more important in order to make processes more reproducible and avoid possible sources of errors right from the beginning. For Thermo Scientific highest quality, consistency and quality control have always been very important and are represented by these HPLC and GC certified kits. The Certified Vial Kits are fully lot-tested including HPLC and GC analysis for 15 critical parameters. The certificate of Conformance is included in every pack.

See all Certified & MS Certified vials & closures.

HPLC & GC Certified Vial Kits (Unassembled and Assembled)

Catalog Vial Glass Patched Cap Septum Vial / Closure Catalog Pack of
Certified Convenience Kit (Unassembled) 9mm wide opening SureStop vials with AVCS caps
CERT5000-575W 2mL Amber Yes Blue Red PTFE/White Silicone C5000-2W
C5000-54B
100
CERT5000-576W 2mL Amber Yes Blue Blue PTFE/White Silicone, Pre-slit C5000-2W
C5000-55B
100
CERT5000-578W 2mL Clear Yes Blue Red PTFE/White Silicone C5000-1W
C5000-54B
100
CERT5000-580W 2mL Clear Yes Blue Ivory PTFE/Red Rubber C5000-1W
C5000-51B
100
CERT5000-582W 2mL Amber Yes Blue Ivory PTFE/Red Rubber C5000-2W
C5000-51B
100
CERT5000-593W 2mL Clear Yes Blue Blue PTFE/White Silicone, Pre-slit C5000-1W
C5000-55B
100
Certified Convenience Kit (Unassembled) 9mm wide opening standard vials with AVCS caps
CERT5000-69LV 350µL Fused Insert Clear Yes Black Bonded Red PTFE/White Silicone C4000-LV1W
C5000-64B
100
CERT5000-72LV 350µL Fused Insert Amber Yes Black Bonded Red PTFE/White Silicone C4000-LV2W
C5000-64B
100
CERT5000-75W 2mL Amber Yes Black Bonded Red PTFE/White Silicone C4000-2W
C5000-64B
100
CERT5000-76W 2mL Amber Yes Gray Bonded Clear PTFE/Clear Silicone, Pre-slit C4000-2W
C5000-75C
100
CERT5000-78W 2mL Clear Yes Black Bonded Red PTFE/White Silicone C4000-1W
C5000-64B
100
CERT5000-79 1.7mL High Recovery Clear No Gray B Bonded Clear PTFE/Clear Silicone, Pre-slit C4000-9
C5000-75C
100
CERT5000-80 2mL Clear No Blue Ivory PTFE/Red Rubber C4000-1
C5000-51B
100
CERT5000-80W 2mL Clear Yes Blue Ivory PTFE/Red Rubber C4000-1W
C5000-51B
100
CERT5000-82W 2mL Amber Yes Blue Ivory PTFE/Red Rubber C4000-2W
C5000-51B
100
CERT5000-92W 2mL Clear Yes Blue Red PTFE/White Silicone C4000-1W
C5000-54B
100
CERT5000-93W 2mL Clear Yes Gray Bonded Clear PTFE/Clear Silicone, Pre-slit C4000-1W
C5000-75C
100
CERT5000-992 1.7mL High Recovery Clear No Black Bonded Red PTFE/White Silicone C4000-9
C5000-64B
100
CERT5000-993 Total Recovery Vial, w/10µL Reservoir Clear No Gray Bonded Clear PTFE/Clear Silicone, Pre-slit C4000-9TR
C5000-75C
100
Certified Kits (Assembled) 9mm wide opening standard vials with AVCS caps
CERT5000-175W 2mL Amber Yes Black Bonded Red PTFE/White Silicone C4000-2W
C5000-64B
100
CERT5000-193W 2mL Clear Yes Gray Bonded Red PTFE/ White Silicone, Pre-slit C4000-1W
C5000-75C
100
CERT5000-176W 2mL Amber Yes Gray Bonded Red PTFE/ White Silicone, Pre-slit C4000-2W
C5000-75C
100

When your instrumentation, sample handling and methodology is pushing the limits, a chromatography vial that can keep up is essential, use the only chromatography vials pre-cleaned to provide unmatched consistency.

  • The first low particle, low background chromatography vials
  • Tested and certified for up to 15 critical physical characteristics affecting vial performance
  • Tested and certified for low background by positive ESI LC/MS and by GC/MS

See all Certified & MS Certified vials & closures.

9mm MS Certified Vial Convenience Kits (Unassembled)
Catalog Vial Glass  Patched Cap Color Septum Pack of
MS Certified Convenience Kits (Unassembled) - SureStop Vials with AVCS Caps
MSCERT5000-34W 2mL SureStop Screw Vial, with AVCS Closure Clear Yes Blue Blue Silicone/PTFE 100
MSCERT5000-35W 2mL SureStop Screw Vial, with AVCS Closure Amber Yes Blue Blue Silicone/PTFE 100
MSCERT5000-40W 2mL SureStop Screw Vial, with AVCS Closure Clear Yes Blue Blue Silicone/PTFE, Pre-slit 100
MSCERT5000-41W 2mL SureStop Screw Vial, with AVCS Closure Amber Yes Blue Blue Silicone/PTFE, Pre-slit 100

Benefits of SureStop Vials – AVCS Caps

How tight should you screw your cap on the vial? How do you avoid misalignments & cap deformities? Remove all doubt by using SureStop Vials with AVCS Caps. This is why:

  1. Prevents cap misalignment
    A leveling feature in the SureStop vial design eliminates cap tilt, which can interfere with autosampler functioning, cause septa deformities, and cause sample evaporation.
  2. Ensures optimal degree of tightening, every time
    The SureStop vial finish incorporates a definite stop point that gives you positive-feedback on when the cap is optimally tightened. This eliminates overtightened or under tightened caps, which can interfere with autosampler functioning, and cause septa deformities and sample evaporation.
AVCS Corrects Misalignments
  1. SureStop/AVCS vial self-aligning cap
  2. Generic vial with cap tilt
  3. Generic vial with dislodged septum
  4. Generic vial with deformed cap
  1. Reduces autosampler interruption, increases autosampler compatibility
    Optimal vial seal compression of SureStop vial-AVCS cap combination
    1. Make vials more compatible with more autosamplers
    2. Have fewer autosampler interruptions due to mishandled vials and vial deformities
  2. Provides an alternative to crimp and snap vials, and bonded caps
    Our tested SureStop vials with AVCS caps offer the performance expected from traditional crimp vials without the need for crimping and decrimping tools. Performance tests reported in this technical note showed that there was less evaporation compared to a crimp vial. Due to the simplicity, reliability and versatility to use the SureStop/AVCS vial-cap system in both GC and LC instruments, you can understand why some customers prefer the easy-to-use SureStop/AVCS vial-cap system to crimped vials.

See how SureStop vials – AVCS caps work

  • How tight should you screw your cap on the vial?
  • How to avoid misalignments & cap deformities


Not sure which vial is right for you?

Not sure which vial is right for you?

Contact with an expert to help you decide.

Speak to a specialist